CCDC174 and EIF4A3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCDC174	EIF4A3
Gene Name		coiled-coil domain containing 174	eukaryotic translation initiation factor 4A3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function		MRNA Binding ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Poly(A) Binding Poly(A) RNA Binding
	Biological Process		Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Splicing, Via Spliceosome RRNA Processing Gene Expression Negative Regulation Of Translation Cytokine-mediated Signaling Pathway Positive Regulation Of Translation Embryonic Cranial Skeleton Morphogenesis MRNA Transport
Pathways			Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Deadenylation of mRNA ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system Antiviral mechanism by IFN-stimulated genes Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: EIF4A3	9 interactors: CASC3 CCDC174 CDCA7L MAGOH NXF1 PDCD4 RBM8A UPF1 YWHAQ
Entrez ID		51244	9775
HPRD ID		12820	06482
Ensembl ID		ENSG00000154781	ENSG00000141543
Uniprot IDs		Q6PII3	P38919
PDB IDs			2HXY 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Embryonic Cranial Skeleton Morphogenesis Positive Regulation Of Translation MRNA 3'-end Processing Negative Regulation Of Translation Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RNA 3'-end Processing MRNA Transport Embryonic Skeletal System Morphogenesis RRNA Processing RRNA Metabolic Process RNA Transport Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Embryonic Skeletal System Development RNA Catabolic Process Ribosome Biogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions	MRNA Transport RNA Transport RNA Localization MRNA Export From Nucleus RNA Export From Nucleus Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Nuclear Export Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Translation Aromatic Compound Catabolic Process Posttranscriptional Regulation Of Gene Expression MRNA Metabolic Process Cellular Localization Regulation Of Alternative MRNA Splicing, Via Spliceosome Cytoplasmic Transport Intracellular Transport Termination Of RNA Polymerase II Transcription Cellular Macromolecule Catabolic Process Regulation Of Gene Expression RNA Splicing Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA-templated Transcription, Termination MRNA Processing Regulation Of Protein Metabolic Process MRNA 3'-end Processing Regulation Of MRNA Processing Regulation Of RNA Splicing RNA 3'-end Processing RNA Processing Transport RNA Metabolic Process Catabolic Process Regulation Of Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Histone MRNA Catabolic Process Poly(A)+ MRNA Export From Nucleus Intracellular MRNA Localization Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination Negative Regulation Of JUN Kinase Activity Dosage Compensation Histone MRNA Metabolic Process
Tagcloud ?			attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592
Tagcloud (Difference) ?			attained chmp4c conceptually dba deg degs domestication dudeg dudegs ehh foxo3 fst homozygosity horse ideas integrating jeju kegg ontology pony rba reads seq thoroughbred thoroughbreds timeless wgs xp znf592
Tagcloud (Intersection) ?