CHCHD2 and IKZF3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CHCHD2	IKZF3
Gene Name		coiled-coil-helix-coiled-coil-helix domain containing 2	IKAROS family zinc finger 3 (Aiolos)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion	Nucleus Cytoplasm Plasma Membrane
	Molecular Function		Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Sequence-specific DNA Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process		Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Mesoderm Development Regulation Of B Cell Proliferation B Cell Activation Regulation Of Apoptotic Process Regulation Of B Cell Differentiation Regulation Of Lymphocyte Differentiation
Pathways
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Primary biliary cirrhosis ( 19458352 23000144 20639880) Rheumatoid arthritis ( 20453842) Systemic lupus erythematosus and Systemic sclerosis ( 23740937) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		12 interactors: ADAMTSL4 EHMT2 GOLGA2 IKZF3 INCA1 KRT31 KRT40 LHX4 REL TCF4 TRIM54 UBC	71 interactors: ABLIM3 AES AKAP9 AQP1 ARMC7 ARNT2 ATPAF2 BCAS2 BCL2L1 C1orf109 CABP5 CDKN1A CDKN2D CHCHD2 CHD3 DGCR6 EFHC1 EMC2 EXOC8 EXOSC5 FANCL FARS2 FBF1 GEM GRB2 HNRNPF HRAS IKZF1 IKZF4 IKZF5 ING5 KAT5 KRT19 LGALS14 LMO1 LMO2 MAGOHB MORN3 MRPL28 MRPL53 NATD1 NEK6 OAZ3 OSGIN1 PCID2 PFDN5 PIK3R2 PIN1 POLM POLR1C PPP1R16B PRKAA1 PRKAB2 PSMA1 RAD51D RBBP8 RCOR3 RHOA SPG21 STAMBPL1 STK16 STX11 TBC1D22B TCAF1 TEKT4 TRAPPC6A TRIM42 TSSK3 TSTD2 UBE2I ZGPAT
Entrez ID		51142	22806
HPRD ID		09879	05869
Ensembl ID		ENSG00000106153
Uniprot IDs		Q9Y6H1	Q9UKT9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Death Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter I-kappaB Kinase/NF-kappaB Signaling Glycogen Metabolic Process Polysaccharide Metabolic Process Negative Regulation Of Cell Death Regulation Of Transcription From RNA Polymerase II Promoter Medial Motor Column Neuron Differentiation Catenin Import Into Nucleus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Energy Reserve Metabolic Process Maintenance Of DNA Repeat Elements DNA Methylation On Cytosine Within A CG Sequence Positive Regulation Of Signal Transduction Glucose Metabolic Process Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Gene Expression Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cell Cycle Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Embryonic Hindgut Morphogenesis Cellular Macromolecule Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Macromolecule Biosynthetic Process Embryonic Genitalia Morphogenesis Regulation Of Cellular Response To Growth Factor Stimulus Somatic Motor Neuron Differentiation Myoblast Fate Commitment Negative Regulation Of Wnt Signaling Pathway Developmental Process Involved In Reproduction Hexose Metabolic Process Secretory Granule Localization Histone H3-K27 Methylation DNA-templated Transcription, Initiation	Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process Organelle Organization Gene Expression Mitotic Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Response To Radiation Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Cellular Response To Organonitrogen Compound Response To Hormone Nucleobase-containing Compound Metabolic Process Cell Cycle Checkpoint RNA Metabolic Process Response To Ionizing Radiation Cell Cycle Arrest Regulation Of Signal Transduction Insulin Receptor Signaling Pathway Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Mitotic Cell Cycle Immune System Process Response To Stress Nitrogen Compound Metabolic Process Signal Transduction In Response To DNA Damage Negative Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Negative Regulation Of Cell Cycle Cellular Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of Signaling Ammonium Transmembrane Transport Biosynthetic Process Macromolecule Biosynthetic Process Neurotrophin TRK Receptor Signaling Pathway Cellular Response To Insulin Stimulus Cellular Response To Organic Substance Response To Organonitrogen Compound
Tagcloud ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Difference) ?			17q12 amplicon cab2 ccct darpp32 endued gc han haplotype histogenesis immumohistochemical implied per1 perld1 ppp1r1b q21 rs11869286 rs1877031 rs881844 rs9972882 sequenom signet stard3 steroidogenic tcap titin tma top2a znfn1a3
Tagcloud (Intersection) ?