RLIM and LDB2

Number of citations of the paper that reports this interaction (PMID 10431247)
31

Data Source:
HPRD (in vitro)

		RLIM	LDB2
Gene Name		ring finger protein, LIM domain interacting	LIM domain binding 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Transcriptional Repressor Complex	Nucleus Transcription Factor Complex
	Molecular Function	Transcription Corepressor Activity Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity	Transcription Cofactor Activity Enzyme Binding LIM Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Random Inactivation Of X Chromosome	Hair Follicle Development Epithelial Structure Maintenance Somatic Stem Cell Maintenance Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS			QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552)
Protein-Protein Interactions		27 interactors: ESR1 ISL1 LDB1 LDB2 LHX1 LHX2 LHX3 LIMK1 LMO2 LNX2 PDLIM1 REXO1 RPS14 SIN3A SMURF2 SNX17 SS18L1 STAT6 STMN1 TERF1 TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2	12 interactors: ISL1 LHX4 LHX9 LMO3 LMO4 RASIP1 RILP RLIM SSBP2 SSBP3 SSBP4 TSNAX
Entrez ID		51132	9079
HPRD ID		02304	16022
Ensembl ID		ENSG00000131263	ENSG00000169744
Uniprot IDs		Q9NVW2	B7Z2D3 E9PFI4 G5E9Y7 O43679
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein K48-linked Ubiquitination Protein Polyubiquitination Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Activation Of Innate Immune Response Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Innate Immune Response RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Protein K11-linked Ubiquitination Negative Regulation Of RNA Biosynthetic Process Cellular Response To Organic Substance Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Stimulus Positive Regulation Of Immune Response Gene Expression Regulation Of Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Regulation Of Immune System Process Regulation Of Innate Immune Response System Development Mitotic Spindle Assembly Checkpoint	Spinal Cord Motor Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Spinal Cord Development Regulation Of Gene Expression Anatomical Structure Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Anatomical Structure Formation Involved In Morphogenesis Regulation Of Metabolic Process Neural Tube Development Motor Neuron Axon Guidance Central Nervous System Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Tissue Morphogenesis RNA Metabolic Process Tube Development Multicellular Organismal Development Cell Differentiation Nervous System Development Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Gonad Morphogenesis Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Random Inactivation Of X Chromosome Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Epithelial Tube Morphogenesis Tissue Development Cardiac Septum Development Axon Guidance Developmental Process Central Nervous System Development System Development Tube Morphogenesis Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Medial Motor Column Neuron Differentiation Positive Regulation Of Anterior Head Development Neural Tube Closure Epithelium Development Negative Regulation Of Transcription, DNA-templated
Tagcloud ?		activators acts clim coactivator deacetylase embryonic encoded enlarge exerts hdac homeodomain inactivation inducer interacts interfering p53 physically playing prevents recruiting repressed repression repressor s1 s4 sin3a sp1 tried	ablated abundant belong belongs brdu crypt endoderm endodermal gut homeobox intestine isl1 isl2 islet1 ldb1 lhx lhx1 lim lineages lmx1a lmx1b mesodermal obligatory patterning prominently quiescent terminally tracing
Tagcloud (Difference) ?		activators acts clim coactivator deacetylase embryonic encoded enlarge exerts hdac homeodomain inactivation inducer interacts interfering p53 physically playing prevents recruiting repressed repression repressor s1 s4 sin3a sp1 tried	ablated abundant belong belongs brdu crypt endoderm endodermal gut homeobox intestine isl1 isl2 islet1 ldb1 lhx lhx1 lineages lmx1a lmx1b mesodermal obligatory patterning prominently quiescent terminally tracing
Tagcloud (Intersection) ?		lim