LDB2 and LMO4

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
HPRD (two hybrid)

		LDB2	LMO4
Gene Name		LIM domain binding 2	LIM domain only 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex	Transcription Factor Complex
	Molecular Function	Transcription Cofactor Activity Enzyme Binding LIM Domain Binding	Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Zinc Ion Binding
	Biological Process	Hair Follicle Development Epithelial Structure Maintenance Somatic Stem Cell Maintenance Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter	Neural Tube Closure Ventricular Septum Development Transcription From RNA Polymerase II Promoter Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Negative Regulation Of Protein Complex Assembly Regulation Of Cell Fate Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Regulation Of Cell Activation
Pathways
Drugs
Diseases
GWAS		QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552)	Response to TNF antagonist treatment ( 18615156) White blood cell types ( 21738478)
Protein-Protein Interactions		12 interactors: ISL1 LHX4 LHX9 LMO3 LMO4 RASIP1 RILP RLIM SSBP2 SSBP3 SSBP4 TSNAX	53 interactors: AES AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675
Entrez ID		9079	8543
HPRD ID		16022	09122
Ensembl ID		ENSG00000169744	ENSG00000143013
Uniprot IDs		B7Z2D3 E9PFI4 G5E9Y7 O43679	P61968
PDB IDs			2L4Z
Enriched GO Terms of Interacting Partners?		Spinal Cord Motor Neuron Differentiation Ventral Spinal Cord Development Cell Differentiation In Spinal Cord Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Spinal Cord Development Regulation Of Gene Expression Anatomical Structure Morphogenesis Regulation Of Nitrogen Compound Metabolic Process Anatomical Structure Formation Involved In Morphogenesis Regulation Of Metabolic Process Neural Tube Development Motor Neuron Axon Guidance Central Nervous System Neuron Differentiation Negative Regulation Of Cellular Metabolic Process Tissue Morphogenesis RNA Metabolic Process Tube Development Multicellular Organismal Development Cell Differentiation Nervous System Development Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Gonad Morphogenesis Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Midbrain-hindbrain Boundary Initiation Prechordal Plate Formation Random Inactivation Of X Chromosome Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Epithelial Tube Morphogenesis Tissue Development Cardiac Septum Development Axon Guidance Developmental Process Central Nervous System Development System Development Tube Morphogenesis Positive Regulation Of Granulocyte Colony-stimulating Factor Production Positive Regulation Of Macrophage Colony-stimulating Factor Production Medial Motor Column Neuron Differentiation Positive Regulation Of Anterior Head Development Neural Tube Closure Epithelium Development Negative Regulation Of Transcription, DNA-templated	Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Tissue Development Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Multicellular Organismal Development Developmental Process Gene Expression Regulation Of Binding Regulation Of Gene Expression Anatomical Structure Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Epithelium Development Negative Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Embryo Development Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Wnt Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Nucleocytoplasmic Transport Embryo Development Ending In Birth Or Egg Hatching Regulation Of Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of DNA Methylation Cell Cycle Somatic Stem Cell Maintenance Regulation Of Protein Binding Anatomical Structure Morphogenesis
Tagcloud ?		ablated abundant belong belongs brdu crypt endoderm endodermal gut homeobox intestine isl1 isl2 islet1 ldb1 lhx lhx1 lim lineages lmx1a lmx1b mesodermal obligatory patterning prominently quiescent terminally tracing	arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Difference) ?		ablated abundant belong belongs brdu crypt endoderm endodermal gut homeobox intestine isl1 isl2 islet1 ldb1 lhx lhx1 lim lineages lmx1a lmx1b mesodermal obligatory patterning prominently quiescent terminally tracing	arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Intersection) ?