TRIM17 and LRSAM1

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM17	LRSAM1
Gene Name		tripartite motif containing 17	leucine rich repeat and sterile alpha motif containing 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Intracellular	Extracellular Region Cytoplasm Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Ubiquitin-protein Transferase Activity Hormone Activity Protein Binding Zinc Ion Binding Ligase Activity
	Biological Process	Protein Autoubiquitination	Protein Polyubiquitination Protein Catabolic Process Negative Regulation Of Endocytosis Viral Budding Protein Autoubiquitination Ubiquitin-dependent Endocytosis
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: LRSAM1 MNAT1 TRAF6 TRIM39 TRIM41 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2N UBE2W USP15	36 interactors: ATXN1 ATXN7 FAM178B GABARAPL2 GPR108 GRIK5 GSK3A KLC1 MDM4 MGAT4B MKRN3 MUTYH MYL2 NINL PHF23 RNF111 RXRG TERF1 TNFRSF10C TRIM17 TRIM74 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2H UBE2J1 UBE2K UBE2N UBE2W UEVLD USP2 USP21 VPS11
Entrez ID		51127	90678
HPRD ID		05839	14325
Ensembl ID		ENSG00000162931	ENSG00000148356
Uniprot IDs		Q9Y577	Q6UWE0
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Cellular Protein Modification Process Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Proteolysis Involved In Cellular Protein Catabolic Process Cellular Macromolecule Catabolic Process Cellular Protein Catabolic Process Cellular Protein Metabolic Process Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Protein Metabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Catabolic Process Protein K11-linked Ubiquitination Positive Regulation Of Innate Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Protein Ubiquitination Proteolysis Regulation Of Innate Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Immune Response-regulating Signaling Pathway Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Protein Ubiquitination Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Oxygen Levels Protein K63-linked Ubiquitination Cellular Response To Stress Positive Regulation Of Immune Response Transforming Growth Factor Beta Receptor Signaling Pathway Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Monoubiquitination Regulation Of Protein Catabolic Process	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Polyubiquitination Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Catabolic Process Regulation Of Protein Catabolic Process Proteolysis Regulation Of Proteasomal Protein Catabolic Process Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Negative Regulation Of Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Protein Metabolic Process Negative Regulation Of Cellular Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Toll-like Receptor Signaling Pathway Mitotic Spindle Assembly Checkpoint Cellular Response To Oxygen Levels Spindle Assembly Checkpoint Cellular Response To Stress Mitotic Spindle Checkpoint Regulation Of Proteolysis Protein Monoubiquitination Negative Regulation Of Chromosome Segregation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Activation Of Innate Immune Response Cellular Metabolic Process Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress
Tagcloud ?		box chains coil coiled conjugated e3 exhibits finger hydrolases interacts ligase polyubiquitin polyubiquitination proteases proteasomal proteasome rendered stabilized susceptible terf trim44 ubch6 ubiquitin ubiquitination ubp usp usps zf
Tagcloud (Difference) ?		box chains coil coiled conjugated e3 exhibits finger hydrolases interacts ligase polyubiquitin polyubiquitination proteases proteasomal proteasome rendered stabilized susceptible terf trim44 ubch6 ubiquitin ubiquitination ubp usp usps zf
Tagcloud (Intersection) ?