PQBP1 and CLTB

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PQBP1	CLTB
Gene Name		polyglutamine binding protein 1	clathrin, light chain B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule	Cytoplasm Trans-Golgi Network Plasma Membrane Clathrin Coat Clathrin Coat Of Trans-Golgi Network Vesicle Clathrin Coat Of Coated Pit Intracellular Membrane-bounded Organelle Ciliary Membrane
	Molecular Function	DNA Binding Transcription Coactivator Activity Ribonucleoprotein Complex Binding	Structural Molecule Activity Protein Binding Peptide Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Neuron Projection Development Regulation Of RNA Splicing Regulation Of Dendrite Morphogenesis	Intracellular Protein Transport Vesicle-mediated Transport
Pathways			Formation of annular gap junctions EPH-ephrin mediated repulsion of cells Axon guidance Gap junction degradation Gap junction trafficking and regulation Gap junction trafficking WNT5A-dependent internalization of FZD4 EPH-Ephrin signaling Signaling by Wnt PCP/CE pathway beta-catenin independent WNT signaling
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		23 interactors: APBB1 APP AQR ATXN1 C14orf1 CLTB EEF1A1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77	7 interactors: CALM1 CLTC CSNK2A1 CSNK2A2 HIP1 HIP1R PQBP1
Entrez ID		10084	1212
HPRD ID		02354	00352
Ensembl ID		ENSG00000102103	ENSG00000175416
Uniprot IDs		O60828	P09497
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Visual Learning Visual Behavior Associative Learning Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Response To Light Stimulus Learning Regulation Of Protein Binding Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cell Division Response To Radiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Respiratory Gaseous Exchange Cell Cycle Regulation Of Neuron Differentiation Regulation Of Binding Learning Or Memory Neurohypophysis Development Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated Cell Cycle Process Negative Regulation Of Neurogenesis Cognition Positive Regulation Of Microtubule Plus-end Binding Collateral Sprouting In Absence Of Injury Golgi Vesicle Fusion To Target Membrane Regulation Of Nitrogen Compound Metabolic Process Mitotic Nuclear Division Response To Abiotic Stimulus Positive Regulation Of Cellular Biosynthetic Process Ribonucleoprotein Complex Biogenesis Mitotic Cell Cycle Process Neuron Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Nucleic Acid-templated Transcription	Regulation Of Cell Division Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Regulation Of Cellular Component Organization Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Regulation Of Cell Cycle Process Negative Regulation Of Chromosome Organization Vesicle-mediated Transport Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Endocytosis Organelle Organization Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Hyaluronan Biosynthetic Process Developmental Process Mitotic Cell Cycle Checkpoint Mitotic Cell Cycle Cell Differentiation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Negative Regulation Of Cellular Protein Metabolic Process Neuron Projection Development Regulation Of Cellular Protein Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Proteasomal Protein Catabolic Process Membrane Organization Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Chromosome Organization Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Protein Metabolic Process Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Regulation Of Protein Metabolic Process Neuron Development Apoptotic Process
Tagcloud ?		amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Difference) ?		amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie
Tagcloud (Intersection) ?