PQBP1 and POU3F2

Number of citations of the paper that reports this interaction (PMID 10332029)
18

Data Source:
BioGRID (two hybrid, affinity chromatography technology)
HPRD (in vivo, two hybrid, in vitro)

		PQBP1	POU3F2
Gene Name		polyglutamine binding protein 1	POU class 3 homeobox 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoplasmic Stress Granule Nuclear Speck Neuronal Ribonucleoprotein Granule	Nucleus Transcription Factor Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Ribonucleoprotein Complex Binding	RNA Polymerase II Transcription Coactivator Activity Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Alternative MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Neuron Projection Development Regulation Of RNA Splicing Regulation Of Dendrite Morphogenesis	Transcription, DNA-templated Positive Regulation Of Cell Proliferation Epidermis Development Astrocyte Development Cerebral Cortex Radially Oriented Cell Migration Forebrain Ventricular Zone Progenitor Cell Division Hypothalamus Cell Differentiation Neurohypophysis Development Myelination In Peripheral Nervous System Neuron Differentiation Positive Regulation Of Multicellular Organism Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Axonogenesis Cellular Response To Organic Substance
Pathways
Drugs
Diseases
GWAS			Brain imaging in schizophrenia (interaction) ( 19023125) Obesity-related traits ( 23251661) QT interval (interaction) ( 23459443)
Protein-Protein Interactions		23 interactors: APBB1 APP AQR ATXN1 C14orf1 CLTB EEF1A1 GOLGA2 HNRNPH2 LNX1 LRIF1 LZTS2 MAPRE1 MED31 POLR2A POU3F2 RAB8A RCVRN SFTPC TLX3 TXNL4A WBP11 WDR77	8 interactors: EP300 GTF2B PAX3 POU3F4 PQBP1 SOX10 SOX11 TBP
Entrez ID		10084	5454
HPRD ID		02354	02734
Ensembl ID		ENSG00000102103	ENSG00000184486
Uniprot IDs		O60828	P20265
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression Visual Learning Visual Behavior Associative Learning Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Response To Light Stimulus Learning Regulation Of Protein Binding Nitrogen Compound Metabolic Process Mitotic Cell Cycle Cell Division Response To Radiation Negative Regulation Of Neuron Differentiation Negative Regulation Of Thymidylate Synthase Biosynthetic Process Respiratory Gaseous Exchange Cell Cycle Regulation Of Neuron Differentiation Regulation Of Binding Learning Or Memory Neurohypophysis Development Synaptic Growth At Neuromuscular Junction Transcription, RNA-templated Cell Cycle Process Negative Regulation Of Neurogenesis Cognition Positive Regulation Of Microtubule Plus-end Binding Collateral Sprouting In Absence Of Injury Golgi Vesicle Fusion To Target Membrane Regulation Of Nitrogen Compound Metabolic Process Mitotic Nuclear Division Response To Abiotic Stimulus Positive Regulation Of Cellular Biosynthetic Process Ribonucleoprotein Complex Biogenesis Mitotic Cell Cycle Process Neuron Differentiation Regulation Of Transcription, DNA-templated Negative Regulation Of Cell Development Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated RNA Biosynthetic Process Transcription From RNA Polymerase II Promoter RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Neural Crest Cell Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Neural Crest Cell Differentiation Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Mesenchymal Cell Development Nitrogen Compound Metabolic Process Mesenchymal Cell Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Embryo Development Nervous System Development Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Mesenchyme Development Positive Regulation Of Macromolecule Biosynthetic Process Tube Development Positive Regulation Of Gene Expression Generation Of Neurons Stem Cell Development Positive Regulation Of Cellular Biosynthetic Process Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Neurogenesis Autonomic Nervous System Development Muscle Organ Development Regulation Of Metabolic Process Neuroepithelial Cell Differentiation Neural Crest Cell Migration Stem Cell Differentiation Central Nervous System Development Transcription Elongation From RNA Polymerase II Promoter Organ Morphogenesis
Tagcloud ?		amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie	200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b
Tagcloud (Difference) ?		amygdala causative cleaved cognition confirming correspondingly dark declined declines efficiently endogenously exploration kd knock maze object obvious ordinary phenylbutyric polyglutamine possessed prefrontal repetitive rescued retardation suppressing syndromic transgene underlie	200a 200b alpl brn1 brn2 callosum cggagac chimpanzee cldn4 crossroads deltaef1 dermo1 facts gastrulation il1 neurulation occupying oct2 sip1 snai1 snai2 twist1 twist2 zeb2 zfhx1a zfhx1b
Tagcloud (Intersection) ?