NONO and IL7R

Number of citations of the paper that reports this interaction (PMID 23151878)
3

Data Source:
BioGRID (unspecified method)

		NONO	IL7R
Gene Name		non-POU domain containing, octamer-binding	interleukin 7 receptor
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Membrane Nuclear Matrix Nuclear Speck Paraspeckles	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Nucleotide Binding Core Promoter Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding	Antigen Binding Interleukin-7 Receptor Activity Protein Binding
	Biological Process	DNA Repair DNA Recombination Transcription, DNA-templated MRNA Processing Circadian Rhythm RNA Splicing Regulation Of Circadian Rhythm Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Regulation Of DNA Recombination Cell Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Immunoglobulin Production Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Size Positive Regulation Of Gene Expression Cell Growth T Cell Differentiation Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7-mediated Signaling Pathway B Cell Proliferation Lymph Node Development Homeostasis Of Number Of Cells
Pathways			Signaling by Interleukins Interleukin-7 signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Multiple sclerosis ( 21244703 19525953 21833088) Primary biliary cirrhosis ( 23000144 21399635) Type 1 diabetes ( 17554260) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		35 interactors: APBB1 AR C11orf68 CA2 DDX6 ERG EWSR1 FXR2 HIST3H3 IL7R IRAK3 LMO4 MAD1L1 NUPR1 ORC5 PIN1 PLEKHF2 POLR2A PPP1CA PPP1CB PPP1CC PRKAA2 PRPF40A PSPC1 PTBP1 SFPQ SMARCB1 SMARCC1 SMARCD1 SPI1 SYNPO TCERG1 WBP4 YLPM1 ZNRD1	104 interactors: ALYREF CIRBP CPSF1 CRLF2 DDX21 DDX39B DDX3X DDX5 DHX36 DHX9 EIF2AK2 ELAVL1 EMG1 FAU FUS FYN G3BP1 GNB2L1 H1FX HIST1H1C HIST1H1E HIST2H2BE HNRNPA0 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPH3 HNRNPL HNRNPR HNRNPU HNRNPUL1 HNRNPUL2 IL2RG IL7 ILF2 ILF3 JAK1 JAK3 KIT LYN MAP4 NCL NONO PABPC1 PABPC4 PABPN1 PIK3R1 PTBP1 PTK2B PTMA PURA PURB QKI RAD21 RBM3 RBMX RPL15 RPL18 RPL22 RPL29 RPL30 RPL31 RPL6 RPL7 RPL8 RPS20 RPS3 RPSA RRAGA RSL1D1 SAFB SF1 SF3A1 SF3B1 SNRNP70 SNRPA SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP14 SRP9 SRSF3 SRSF9 SSB STAT3 STAT5A STAT5B SYNCRIP TOE1 TOP1 TSLP U2AF1 U2AF2 YBX1 YBX3 YWHAE YWHAG ZNF787
Entrez ID		4841	3575
HPRD ID		02098	00893
Ensembl ID		ENSG00000147140	ENSG00000168685
Uniprot IDs		Q15233	D6RGV2 D9N160 P16871
PDB IDs		3SDE	3DI2 3DI3 3UP1
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression RNA Metabolic Process Gene Expression Regulation Of Circadian Rhythm Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Nucleosome Disassembly Cellular Macromolecule Biosynthetic Process Cellular Metabolic Process Macromolecule Biosynthetic Process Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Triglyceride Catabolic Process Rhythmic Process Photoperiodism Entrainment Of Circadian Clock Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Acylglycerol Catabolic Process Cell Cycle Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Chromatin Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Glycogen Catabolic Process Energy Reserve Metabolic Process Chromatin Organization Chromosome Organization Biosynthetic Process Regulation Of Cellular Process Glycogen Metabolic Process MRNA Metabolic Process RNA Splicing Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Generation Of Precursor Metabolites And Energy Transcription From RNA Polymerase II Promoter Circadian Regulation Of Gene Expression Positive Regulation Of Gene Expression Regulation Of Cellular Component Organization Polysaccharide Metabolic Process	MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Viral Process RNA Biosynthetic Process SRP-dependent Cotranslational Protein Targeting To Membrane Termination Of RNA Polymerase II Transcription Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Macromolecule Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Posttranscriptional Regulation Of Gene Expression MRNA Stabilization RNA 3'-end Processing MRNA 3'-end Processing RNA Catabolic Process Viral Transcription Cellular Metabolic Process Protein Targeting To Membrane DNA-templated Transcription, Termination Protein Targeting Nuclear-transcribed MRNA Catabolic Process Establishment Of Protein Localization To Organelle MRNA Catabolic Process Ribonucleoprotein Complex Assembly Regulation Of Translation Ribonucleoprotein Complex Biogenesis Biosynthetic Process Protein Localization To Organelle Translational Termination Establishment Of Protein Localization To Membrane Intracellular Transport Translational Elongation
Tagcloud ?		acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		acth adrenal adrenocortical adrenocorticotropin belongs biosynthesis camp confers cortisol cyp17a1 dbhs exoribonuclease export facilitating glucocorticoid h295r isoforms p54nrb pde pde11a pde2a pde3a pde3b pde4a pde4d phosphodiesterase select splicing xrn2	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?