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LINC01554 and MCM7
Number of citations of the paper that reports this interaction (PubMedID
30809309
)
42
Data Source:
BioGRID
(unspecified method)
LINC01554
MCM7
Description
long intergenic non-protein coding RNA 1554
minichromosome maintenance complex component 7
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Membrane
MCM Complex
CMG Complex
Molecular Function
Nucleotide Binding
DNA Binding
DNA Helicase Activity
Single-stranded DNA Binding
Helicase Activity
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Single-stranded DNA Helicase Activity
Biological Process
Double-strand Break Repair Via Break-induced Replication
DNA Replication
DNA Replication Initiation
DNA Strand Elongation Involved In DNA Replication
DNA Damage Response
Cell Population Proliferation
Response To Xenobiotic Stimulus
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Phosphorylation
Cellular Response To Epidermal Growth Factor Stimulus
Cellular Response To Xenobiotic Stimulus
Pathways
Activation of ATR in response to replication stress
Unwinding of DNA
Assembly of the pre-replicative complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
Switching of origins to a post-replicative state
Drugs
Diseases
GWAS
LDL cholesterol levels in HIV infection (
33109212
)
Brain morphology (MOSTest) (
32665545
)
Refractive error (
32231278
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
141 interacting genes:
AARS1
ACADVL
ACIN1
ACTB
ACTG1
ACTN1
ACTN3
ACTR3
ALDOA
ANXA2
ANXA5
ANXA6
APEX1
ARHGAP1
ASS1
ATAD3A
ATIC
ATP5F1A
BZW2
CANX
CCT2
CCT3
CCT4
CCT6A
CCT7
CKAP4
CS
CTPS1
DDX3X
DDX46
DHX9
DNAH2
DNAJA1
DST
DYNC1H1
EDARADD
EEF1G
EEF2
EIF3A
EIF3E
EIF4A2
EIF4B
ENO1
ENO3
EPRS1
ERO1A
G3BP1
G6PD
GANAB
GAPDH
GARS1
GDI2
GPI
GTF2I
HIVEP2
HMCN1
HNRNPF
HSP90AA1
HSP90B1
HSPA1L
HSPA5
HSPA8
HSPA9
HSPD1
HYOU1
IDH1
IPO4
IPO7
IPO9
ITPR2
KARS1
KPNA1
KPNB1
KRT18
KRT7
KRT8
KRT8P3
LRPPRC
MCM7
MSN
MYO18A
NAP1L1
NAP1L4
NCBP1
NCL
NPM1
OLA1
OXCT1
PABPC1
PCBP2
PDIA3
PDIA6
PFAS
PGD
PGK1
PGM1
PHGDH
PKM
PLOD2
PMPCA
POR
PPP2R1A
PSMC1
PSMD2
PSMD7
PTBP1
RDX
RPL6
RPSA
RTCB
RTN4
SARS1
SEPTIN7
SEPTIN9
SERPINH1
SFPQ
SQSTM1
TARS1
TGFBI
THOP1
TKT
TTF2
TUBA1A
TUBA8
TUBB
TUBB2A
TUBB3
TUBB4A
TUBB4B
TUBB6
TUFM
TXNRD1
TYMP
UBA1
VCL
VCP
VIM
VPS35
WARS1
XPO1
XRCC5
79 interacting genes:
ABI2
AK8
APP
ASB8
C8orf34
CCDC102B
CCND1
CCNH
CDC42
CDC45
CDC6
CDC7
CDK7
CDKN1B
CEBPA
CEP68
CHEK1
COG6
CRLS1
CRYAA
DBF4
DNAAF6
DUX4
ELOC
ESCO2
FHL2
GOLGA2
H3-4
HIF1A
IKBKG
IKZF3
INTS6
KIFC3
LINC01554
LNX2
LRR1
MAGEA6
MBIP
MCM10
MCM2
MCM3
MCM4
MCM5
MCM6
MCM8
MEOX2
MIPOL1
MNAT1
NAB2
NFKBIA
ORC1
ORC2
ORC3
ORC4
ORC5
ORC6
PLK1
PNMA1
RAD17
RB1
RBL1
RBL2
RBM8A
RBPMS
RINT1
RNF181
RPA1
SMC1A
SNTA1
SP2
SSX2IP
TFIP11
TREX1
TRIM27
TRIM54
TRIM63
UBE3A
UBQLN1
USHBP1
Entrez ID
202299
4176
HPRD ID
16896
01154
Ensembl ID
ENSG00000236882
ENSG00000166508
Uniprot IDs
A0A0S2Z4A5
C6EMX8
C9J8M6
P33993
PDB IDs
6XTX
6XTY
7PFO
7PLO
7W1Y
7W68
8B9D
8RWV
8S09
8S0A
8S0B
8S0D
8S0E
8S0F
8W0E
8W0F
8W0G
8W0I
9CAQ
Enriched GO Terms of Interacting Partners
?
Extracellular Exosome
RNA Binding
Nucleotide Binding
Cytosol
Cytoplasm
Unfolded Protein Binding
ATP-dependent Protein Folding Chaperone
ATP Hydrolysis Activity
ATP Binding
Focal Adhesion
Protein Folding
Secretory Granule Lumen
Cadherin Binding
Ficolin-1-rich Granule Lumen
Protein Folding Chaperone
Structural Constituent Of Cytoskeleton
Nucleotide Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Microtubule
Ubiquitin Protein Ligase Binding
Nucleobase-containing Compound Metabolic Process
Ligase Activity
Melanosome
Purine Nucleotide Metabolic Process
Nucleoside Phosphate Metabolic Process
Protein Refolding
Nucleobase-containing Small Molecule Metabolic Process
Glycolytic Process
Positive Regulation Of Telomerase RNA Localization To Cajal Body
Ribose Phosphate Metabolic Process
ADP Catabolic Process
Positive Regulation Of Protein Localization To Cajal Body
Chaperonin-containing T-complex
ATP Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoprotein Complex
Ribonucleoside Diphosphate Catabolic Process
ADP Metabolic Process
Nucleotide Catabolic Process
Nucleoside Diphosphate Catabolic Process
TRNA Aminoacylation For Protein Translation
Aminoacyl-tRNA Ligase Activity
Ribonucleotide Metabolic Process
Microtubule Cytoskeleton
Protein Folding In Endoplasmic Reticulum
Regulation Of Telomerase RNA Localization To Cajal Body
Positive Regulation Of Telomere Maintenance Via Telomerase
Nucleobase-containing Compound Catabolic Process
Translation
TRNA Aminoacylation
DNA Replication Initiation
DNA Replication
DNA Replication Origin Binding
DNA Metabolic Process
Nuclear Origin Of Replication Recognition Complex
Chromosome, Telomeric Region
Nucleoplasm
Regulation Of DNA Replication
Origin Recognition Complex
Double-strand Break Repair Via Break-induced Replication
Nucleus
DNA Damage Response
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle Phase Transition
CMG Complex
MCM Complex
Regulation Of Mitotic Cell Cycle
Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleic Acid Metabolic Process
Negative Regulation Of Cell Cycle
Single-stranded DNA Binding
Regulation Of Cell Cycle Process
DNA Repair
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Cell Cycle
Negative Regulation Of Cell Cycle Process
Negative Regulation Of Cell Cycle Phase Transition
Double-strand Break Repair Via Homologous Recombination
Regulation Of DNA Metabolic Process
Cellular Response To Stress
Recombinational Repair
Mitotic DNA Integrity Checkpoint Signaling
Chromosome
Nucleobase-containing Compound Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Double-strand Break Repair
Regulation Of DNA-templated DNA Replication Initiation
Regulation Of Cell Cycle G1/S Phase Transition
DNA Recombination
Single-stranded DNA Helicase Activity
Regulation Of Primary Metabolic Process
Regulation Of G2/M Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G2/M Phase Transition
Transcription Factor TFIIK Complex
Mitotic G2/M Transition Checkpoint
CAK-ERCC2 Complex
Mitotic DNA Replication Initiation
Regulation Of Lipid Kinase Activity
Macromolecule Metabolic Process
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