LINC01554 and EIF4B

Number of citations of the paper that reports this interaction (PubMedID 30809309)
42

Data Source:
BioGRID (unspecified method)

		LINC01554	EIF4B
Description		long intergenic non-protein coding RNA 1554	eukaryotic translation initiation factor 4B
Image		No pdb structure
GO Annotations	Cellular Component		Cytosol Eukaryotic Translation Initiation Factor 4F Complex
	Molecular Function		Nucleic Acid Binding RNA Binding Translation Initiation Factor Activity Protein Binding RNA Strand Annealing Activity RNA Strand-exchange Activity Ribosomal Small Subunit Binding
	Biological Process		Formation Of Translation Preinitiation Complex Translation Translational Initiation Regulation Of Translational Initiation Eukaryotic Translation Initiation Factor 4F Complex Assembly
Pathways			L13a-mediated translational silencing of Ceruloplasmin expression mTORC1-mediated signalling Deadenylation of mRNA Deadenylation of mRNA Translation initiation complex formation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit M-decay: degradation of maternal mRNAs by maternally stored factors Z-decay: degradation of maternal mRNAs by zygotically expressed factors
Drugs
Diseases
GWAS		LDL cholesterol levels in HIV infection ( 33109212)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Prostate cancer ( 21743057)
Interacting Genes		141 interacting genes: AARS1 ACADVL ACIN1 ACTB ACTG1 ACTN1 ACTN3 ACTR3 ALDOA ANXA2 ANXA5 ANXA6 APEX1 ARHGAP1 ASS1 ATAD3A ATIC ATP5F1A BZW2 CANX CCT2 CCT3 CCT4 CCT6A CCT7 CKAP4 CS CTPS1 DDX3X DDX46 DHX9 DNAH2 DNAJA1 DST DYNC1H1 EDARADD EEF1G EEF2 EIF3A EIF3E EIF4A2 EIF4B ENO1 ENO3 EPRS1 ERO1A G3BP1 G6PD GANAB GAPDH GARS1 GDI2 GPI GTF2I HIVEP2 HMCN1 HNRNPF HSP90AA1 HSP90B1 HSPA1L HSPA5 HSPA8 HSPA9 HSPD1 HYOU1 IDH1 IPO4 IPO7 IPO9 ITPR2 KARS1 KPNA1 KPNB1 KRT18 KRT7 KRT8 KRT8P3 LRPPRC MCM7 MSN MYO18A NAP1L1 NAP1L4 NCBP1 NCL NPM1 OLA1 OXCT1 PABPC1 PCBP2 PDIA3 PDIA6 PFAS PGD PGK1 PGM1 PHGDH PKM PLOD2 PMPCA POR PPP2R1A PSMC1 PSMD2 PSMD7 PTBP1 RDX RPL6 RPSA RTCB RTN4 SARS1 SEPTIN7 SEPTIN9 SERPINH1 SFPQ SQSTM1 TARS1 TGFBI THOP1 TKT TTF2 TUBA1A TUBA8 TUBB TUBB2A TUBB3 TUBB4A TUBB4B TUBB6 TUFM TXNRD1 TYMP UBA1 VCL VCP VIM VPS35 WARS1 XPO1 XRCC5	20 interacting genes: ACD CASP3 CEBPA CSNK2A1 EIF3A EIF4E LAMTOR5 LINC01554 PABPC1 PAK2 POT1 PRKN RHOU RPS6KB1 SFN SMAD3 SRPK2 TERF1 TINF2 USP11
Entrez ID		202299	1975
HPRD ID		16896	04892
Ensembl ID		ENSG00000236882	ENSG00000063046
Uniprot IDs			B4DRM3 E7EX17 P23588 Q7Z5Y0
PDB IDs			1WI8 2J76 6FEC
Enriched GO Terms of Interacting Partners?		Extracellular Exosome RNA Binding Nucleotide Binding Cytosol Cytoplasm Unfolded Protein Binding ATP-dependent Protein Folding Chaperone ATP Hydrolysis Activity ATP Binding Focal Adhesion Protein Folding Secretory Granule Lumen Cadherin Binding Ficolin-1-rich Granule Lumen Protein Folding Chaperone Structural Constituent Of Cytoskeleton Nucleotide Metabolic Process Nicotinamide Nucleotide Metabolic Process Microtubule Ubiquitin Protein Ligase Binding Nucleobase-containing Compound Metabolic Process Ligase Activity Melanosome Purine Nucleotide Metabolic Process Nucleoside Phosphate Metabolic Process Protein Refolding Nucleobase-containing Small Molecule Metabolic Process Glycolytic Process Positive Regulation Of Telomerase RNA Localization To Cajal Body Ribose Phosphate Metabolic Process ADP Catabolic Process Positive Regulation Of Protein Localization To Cajal Body Chaperonin-containing T-complex ATP Metabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Ribonucleoprotein Complex Ribonucleoside Diphosphate Catabolic Process ADP Metabolic Process Nucleotide Catabolic Process Nucleoside Diphosphate Catabolic Process TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Ribonucleotide Metabolic Process Microtubule Cytoskeleton Protein Folding In Endoplasmic Reticulum Regulation Of Telomerase RNA Localization To Cajal Body Positive Regulation Of Telomere Maintenance Via Telomerase Nucleobase-containing Compound Catabolic Process Translation TRNA Aminoacylation	Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Telomeric DNA Binding Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Metabolic Process Response To Glucocorticoid Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Metabolic Process Response To Corticosteroid Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Telomere Maintenance Telomere Maintenance Via Telomerase Negative Regulation Of Chromosome Organization Negative Regulation Of Biosynthetic Process Execution Phase Of Apoptosis RNA-templated DNA Biosynthetic Process Regulation Of DNA Biosynthetic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Response To Steroid Hormone Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Macromolecule Metabolic Process Positive Regulation Of Chromosome Organization Organelle Organization Regulation Of Telomere Maintenance Positive Regulation Of Macromolecule Metabolic Process Telomere Organization Intracellular Signal Transduction Regulation Of Cell Cycle Response To Dexamethasone Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Organelle Organization Regulation Of Establishment Of Protein Localization To Chromosome Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization Positive Regulation Of Metabolic Process Cellular Component Assembly Regulation Of Macromolecule Metabolic Process DEAD/H-box RNA Helicase Binding Regulation Of Macromolecule Biosynthetic Process Nucleus
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