MYOC and FUBP1

Number of citations of the paper that reports this interaction (PMID 16289162)
20

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		MYOC	FUBP1
Gene Name		myocilin, trabecular meshwork inducible glucocorticoid response	far upstream element (FUSE) binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Proteinaceous Extracellular Matrix Extracellular Space Mitochondrial Outer Membrane Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Endoplasmic Reticulum Rough Endoplasmic Reticulum Golgi Apparatus Cilium Cytoplasmic Membrane-bounded Vesicle Extracellular Matrix Cytoplasmic Vesicle Node Of Ranvier Extracellular Vesicular Exosome	Nucleus Nucleoplasm
	Molecular Function	Fibronectin Binding Frizzled Binding Protein Binding Receptor Tyrosine Kinase Binding Myosin Light Chain Binding	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Osteoblast Differentiation Negative Regulation Of Cell-matrix Adhesion Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Skeletal Muscle Hypertrophy Myelination In Peripheral Nervous System Positive Regulation Of Cell Migration Neuron Projection Development Negative Regulation Of Rho Protein Signal Transduction Non-canonical Wnt Signaling Pathway Via JNK Cascade ERBB2-ERBB3 Signaling Pathway Regulation Of MAPK Cascade Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Stress Fiber Assembly Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Depolarization Bone Development Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		40 interactors: A2M ACTA2 ACTB ACTG1 ALDOA ANXA2 C1QB CAP1 CD81 CKM CLIC1 COL1A2 COL3A1 ECE1 EEF1A1 ENO1 FBN1 FN1 FTL FUBP1 GAPDH GGTLC1 HAGH IGLL1 ITGA7 LAMA5 LGALS3 MAEA MYL2 NOTCH2 OLFM3 OLFML3 PKLR PKM RFC1 SERPINF1 TGFBR1 TIMP1 TKT TNFRSF1A	13 interactors: AIMP2 CCNH CELF1 CHD3 CRMP1 GTF2H1 IMMT MAPK14 MYOC PUF60 SMN1 TLE1 VIM
Entrez ID		4653	8880
HPRD ID		03387	10349
Ensembl ID		ENSG00000034971	ENSG00000162613
Uniprot IDs		Q99972	B4DT31 Q96AE4
PDB IDs			1J4W 2KXH
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Platelet Activation Extracellular Matrix Disassembly Cell Activation Response To Wounding Blood Coagulation Regulation Of Body Fluid Levels Hemostasis Wound Healing Cardiovascular System Development Collagen Fibril Organization System Development Developmental Process Blood Vessel Development Platelet Degranulation Multicellular Organismal Development Vasculature Development Glycolytic Process Organ Development Pyruvate Metabolic Process Pathogenesis Anatomical Structure Development Response To Stress Anatomical Structure Morphogenesis Monosaccharide Metabolic Process Carbohydrate Catabolic Process Locomotion Cell Development Glucose Metabolic Process Cell Differentiation Regulation Of Cellular Component Movement Vesicle-mediated Transport Response To Stimulus Movement Of Cell Or Subcellular Component Hexose Metabolic Process Immune System Process Monocarboxylic Acid Metabolic Process Carboxylic Acid Metabolic Process Skeletal System Development Platelet Aggregation Generation Of Precursor Metabolites And Energy Blood Vessel Morphogenesis Secretion Regulation Of Cell Motility Regulation Of Immune Response Organic Acid Metabolic Process Tissue Development Regulation Of Locomotion Cell Adhesion	MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Nitrogen Compound Metabolic Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Regulation Of Gene Expression, Epigenetic Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Spliceosomal Complex Assembly Transcription Elongation From RNA Polymerase II Promoter ERBB2-ERBB3 Signaling Pathway P38MAPK Cascade Skeletal Muscle Hypertrophy Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Termination Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic RNA Splicing Positive Regulation Of Gene Expression RNA Biosynthetic Process DNA-templated Transcription, Elongation Regulation Of Metabolic Process Nucleotide-excision Repair ERBB2 Signaling Pathway Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Apoptotic Process Regulation Of Gene Expression Anatomical Structure Development Macromolecule Biosynthetic Process Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Programmed Cell Death Cell Death Death Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process
Tagcloud ?		accessible applicability atomic biomedically bladed broader continue deciphering detail differentiating distinctive divergent glaucoma glycerol hubs hydrophilic inherited mapped movements myocilin ocular olf olfactomedin onto overlapping propellers pursuit solved synonymous	19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast
Tagcloud (Difference) ?		accessible applicability atomic biomedically bladed broader continue deciphering detail differentiating distinctive divergent glaucoma glycerol hubs hydrophilic inherited mapped movements myocilin ocular olf olfactomedin onto overlapping propellers pursuit solved synonymous	19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast
Tagcloud (Intersection) ?