FUBP1 and CCNH

Number of citations of the paper that reports this interaction (PMID 11239393)
31

Data Source:
HPRD (in vitro)

		FUBP1	CCNH
Gene Name		far upstream element (FUSE) binding protein 1	cyclin H
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm Holo TFIIH Complex Cyclin-dependent Protein Kinase Activating Kinase Holoenzyme Complex TFIIK Complex
	Molecular Function	RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Poly(A) RNA Binding	Protein Binding DNA-dependent ATPase Activity RNA Polymerase II Carboxy-terminal Domain Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity Protein Kinase Binding
	Biological Process	Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal DNA Repair Transcription-coupled Nucleotide-excision Repair Nucleotide-excision Repair Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Protein Phosphorylation Gene Expression Viral Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Viral Transcription
Pathways			RNA Polymerase II Promoter Escape Formation of HIV-1 elongation complex containing HIV-1 Tat RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Tat-mediated elongation of the HIV-1 transcript Cyclin E associated events during G1/S transition Formation of transcription-coupled NER (TC-NER) repair complex Dual incision reaction in TC-NER NoRC negatively regulates rRNA expression G1/S Transition Mitotic G1-G1/S phases S Phase Late Phase of HIV Life Cycle Formation of RNA Pol II elongation complex Global Genomic NER (GG-NER) RNA Polymerase II Transcription Initiation And Promoter Clearance Cyclin A:Cdk2-associated events at S phase entry Mitotic G2-G2/M phases Transcription of the HIV genome Nucleotide Excision Repair RNA Polymerase II Transcription RNA Polymerase I Transcription Initiation HIV Infection RNA Polymerase I Promoter Clearance Formation of the Early Elongation Complex G2/M Transition RNA Pol II CTD phosphorylation and interaction with CE RNA Polymerase II Pre-transcription Events HIV Transcription Initiation HIV Life Cycle RNA Pol II CTD phosphorylation and interaction with CE Cyclin A/B1 associated events during G2/M transition RNA Polymerase II HIV Promoter Escape HIV Transcription Elongation Dual incision reaction in GG-NER RNA Polymerase I Transcription mRNA Capping RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination G1 Phase Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression Cell Cycle, Mitotic Cyclin D associated events in G1 Transcription-coupled NER (TC-NER) Formation of HIV elongation complex in the absence of HIV Tat Formation of the HIV-1 Early Elongation Complex Formation of incision complex in GG-NER RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Elongation
Drugs
Diseases
GWAS			Major depressive disorder ( 23377640)
Protein-Protein Interactions		13 interactors: AIMP2 CCNH CELF1 CHD3 CRMP1 GTF2H1 IMMT MAPK14 MYOC PUF60 SMN1 TLE1 VIM	39 interactors: AR CALCOCO2 CCDC170 CCDC33 CCNC CDK2 CDK20 CDK7 CDK8 CSNK2B CTBP2 CTD DUSP12 ERCC3 ESR1 FUBP1 GANAB GOLGA2 GTF2E2 GTF2H1 KLC3 MBP MCM7 MNAT1 MTA1 MYC NDC80 NEDD4 POLR2A POLR2B PPFIA1 PSMA1 RARB SFN SSSCA1 SSX2IP SUPT5H TP53 TRIM8
Entrez ID		8880	902
HPRD ID		10349	09059
Ensembl ID		ENSG00000162613	ENSG00000134480
Uniprot IDs		B4DT31 Q96AE4	P51946
PDB IDs		1J4W 2KXH	1JKW 1KXU
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Metabolic Process RNA Processing Nucleobase-containing Compound Metabolic Process Gene Expression Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nucleotide-excision Repair, DNA Damage Removal Nitrogen Compound Metabolic Process Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter 7-methylguanosine MRNA Capping Transcription From RNA Polymerase I Promoter 7-methylguanosine RNA Capping Regulation Of Gene Expression, Epigenetic Transcription-coupled Nucleotide-excision Repair Positive Regulation Of Viral Transcription Spliceosomal Complex Assembly Transcription Elongation From RNA Polymerase II Promoter ERBB2-ERBB3 Signaling Pathway P38MAPK Cascade Skeletal Muscle Hypertrophy Regulation Of Viral Transcription Positive Regulation Of Viral Process DNA-templated Transcription, Termination Transcription, DNA-templated Negative Regulation Of Gene Expression, Epigenetic RNA Splicing Positive Regulation Of Gene Expression RNA Biosynthetic Process DNA-templated Transcription, Elongation Regulation Of Metabolic Process Nucleotide-excision Repair ERBB2 Signaling Pathway Multicellular Organismal Development Cellular Macromolecule Biosynthetic Process Apoptotic Process Regulation Of Gene Expression Anatomical Structure Development Macromolecule Biosynthetic Process Glial Cell Development Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Programmed Cell Death Cell Death Death Regulation Of Transcription From RNA Polymerase II Promoter DNA Catabolic Process	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter 7-methylguanosine MRNA Capping Transcription Elongation From RNA Polymerase II Promoter 7-methylguanosine RNA Capping Regulation Of Viral Transcription DNA-templated Transcription, Elongation Positive Regulation Of Viral Transcription Viral Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Viral Process Positive Regulation Of Cellular Biosynthetic Process Transcription-coupled Nucleotide-excision Repair Regulation Of Viral Process Nucleotide-excision Repair Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Response To DNA Damage Stimulus Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Cell Cycle Cellular Response To Stress Nucleotide-excision Repair, DNA Damage Removal Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Cell Cycle Gene Expression Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of RNA Biosynthetic Process Mitotic Cell Cycle Transcription Initiation From RNA Polymerase I Promoter Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription From RNA Polymerase I Promoter DNA Repair Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Negative Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Heterocycle Metabolic Process Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast	carrying chemotherapy conversely ercc5 ercc6 genotype genotypes genotyping good homozygous hrs longer median mms19l months os osteosarcoma pfs polymorphisms poor rflp rs1047768 rs17655 rs29001322 shorter tt undergoing xpc
Tagcloud (Difference) ?		19q 1p anaplastic arms astrocytic astrocytoma atrx cdkn2a cic displays endogenously expresses gliomas histopathology hydroxyglutarate idh1 infiltrating investigating isocitrate jhh ketoglutarate lengthening oligodendrocytic r132h scarcity subgroup telomeres unfortunately vast	carrying chemotherapy conversely ercc5 ercc6 genotype genotypes genotyping good homozygous hrs longer median mms19l months os osteosarcoma pfs polymorphisms poor rflp rs1047768 rs17655 rs29001322 shorter tt undergoing xpc
Tagcloud (Intersection) ?