MYLK and GOPC

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MYLK	GOPC
Gene Name		myosin light chain kinase	golgi-associated PDZ and coiled-coil motif containing
Image
Gene Ontology Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cell-cell Junction Lamellipodium Cleavage Furrow Extracellular Vesicular Exosome	Golgi Membrane Cytoplasm Golgi Apparatus Plasma Membrane Postsynaptic Density Membrane Cell Junction Trans-Golgi Network Transport Vesicle Dendrite Protein Complex Postsynaptic Membrane
	Molecular Function	Actin Binding Calmodulin-dependent Protein Kinase Activity Myosin Light Chain Kinase Activity Protein Binding Calmodulin Binding ATP Binding Metal Ion Binding	Small GTPase Regulator Activity Frizzled Binding Protein Binding Protein C-terminus Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Protein Phosphorylation Muscle Contraction Smooth Muscle Contraction Actin Filament Organization Tonic Smooth Muscle Contraction Positive Regulation Of Cell Migration Bleb Assembly Positive Regulation Of Calcium Ion Transport Aorta Smooth Muscle Tissue Morphogenesis Cellular Hypotonic Response Positive Regulation Of Wound Healing	ER To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Spermatid Nucleus Differentiation Protein Transport Cytoplasmic Sequestering Of CFTR Protein Apical Protein Localization Regulation Of Catalytic Activity Protein Homooligomerization
Pathways		Smooth Muscle Contraction
Drugs
Diseases
GWAS			Colorectal cancer ( 23266556)
Protein-Protein Interactions		13 interactors: ACTA1 ACTC1 CALM1 CAMK2G CTTN GOPC MAPK3 MLC1 PAK1 PAK2 PRKCA PRKG2 SRC	58 interactors: ABCA1 ADRB1 AKIRIN1 ASIC3 BATF BECN1 C17orf67 CCDC102B CD300C CDC42 CDKN2C CERCAM CFTR CLCN3 CSPG5 DPYD FAM90A1 FAM9B FOSL2 FZD5 FZD8 GOLGA3 GRID1 GRID2 HCK IGHG3 JUN KPNA1 LCLAT1 MORN4 MRPL1 MUM1 MYLK MYOCD NUP62 PARK7 PID1 RELA RHOQ RNF183 RNF220 RPL13AP17 RTKN SEMA4G SLC25A18 SPATA8 SSNA1 SSTR5 STARD3 STX6 TGFBR2 VIM VTN ZBTB49 ZNF564 ZNF581 ZNF587 ZSCAN1
Entrez ID		4638	57120
HPRD ID		02952	06024
Ensembl ID		ENSG00000065534	ENSG00000047932
Uniprot IDs		B4DUE3 Q15746 Q6P2N0	Q9HD26
PDB IDs		2CQV 2K0F 2YR3	2DC2 2LOB 4E34 4E35
Enriched GO Terms of Interacting Partners?		Protein Autophosphorylation Vascular Endothelial Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Innate Immune Response Fc Receptor Signaling Pathway Wound Healing Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity Response To Abiotic Stimulus Actin Filament-based Process Actin-myosin Filament Sliding Muscle Filament Sliding Cell Differentiation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Organic Substance Response To Wounding Cell Development Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Phosphorylation Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Cellular Amino Acid Metabolic Process Cellular Component Assembly Epidermal Growth Factor Receptor Signaling Pathway Anatomical Structure Development Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Actin-mediated Cell Contraction Immune Response Regulation Of Kinase Activity Protein Phosphorylation Blood Coagulation Hemostasis Defense Response Regulation Of Intracellular Transport Caveolin-mediated Endocytosis Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Peptidyl-serine Autophosphorylation Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Kinase Activity Positive Regulation Of Protein Modification Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Muscle Contraction	Cellular Response To Stimulus Cellular Response To Organic Substance Response To External Stimulus Myeloid Leukocyte Differentiation Leukocyte Differentiation Response To Organic Substance Cell Surface Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Regulation Of Protein Phosphorylation Response To Stimulus Cellular Process Cell Communication Positive Regulation Of Cellular Biosynthetic Process Regulation Of Binding Positive Regulation Of Transport Regulation Of Cellular Process Cell Differentiation Regulation Of Membrane Potential Myeloid Dendritic Cell Differentiation Cellular Response To Hormone Stimulus Signal Transduction Blood Vessel Morphogenesis Myeloid Dendritic Cell Activation Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of DNA Binding Response To Extracellular Stimulus Negative Regulation Of Protein Phosphorylation Cell Death Death Positive Regulation Of Gene Expression T-helper 17 Cell Lineage Commitment Response To Lipid Regulation Of Phosphorylation Cellular Localization Membrane Hyperpolarization Negative Regulation Of Cell Proliferation Defense Response Regulation Of Signaling Response To Drug Positive Regulation Of DNA Binding Blood Vessel Development Response To Mechanical Stimulus Response To Stress Signaling Response To Cytokine T-helper 17 Cell Differentiation Dendritic Cell Differentiation Response To Other Organism
Tagcloud ?		bioinformatics bmp2 calm1 cnaq csf2rb csf3 expressions fifteen gria2 il10ra il10rb il11ra il3ra il6st lifr lymphatic microarrays myl9 myosin nonsmokers nsclc paraneoplastic pathohistological plcb4 ppp2ca rac3 rock2 thbs1 verify	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
Tagcloud (Difference) ?		bioinformatics bmp2 calm1 cnaq csf2rb csf3 expressions fifteen gria2 il10ra il10rb il11ra il3ra il6st lifr lymphatic microarrays myl9 myosin nonsmokers nsclc paraneoplastic pathohistological plcb4 ppp2ca rac3 rock2 thbs1 verify	admissions attained clinicaltrials clinics dbp empowering empowerment equation estimating estimation generalized gov hba1c hong inpatient kong nct01935349 outpatient pep programme registration sbp september service sopc specialist t2dm utilization visits
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