CIITA and TAF9

Number of citations of the paper that reports this interaction (PMID 9177216)
28

Data Source:
BioGRID (pull down)

		CIITA	TAF9
Gene Name		class II, major histocompatibility complex, transactivator	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm PML Body	PCAF Complex Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex Pre-snoRNP Complex MLL1 Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding ATP Binding GTP Binding Protein C-terminus Binding Kinase Activity Transferase Activity, Transferring Acyl Groups Protein Complex Binding Activating Transcription Factor Binding Transcription Regulatory Region DNA Binding	P53 Binding DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Activating Transcription Factor Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity C2H2 Zinc Finger Domain Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Immune Response Phosphorylation Cytokine-mediated Signaling Pathway Negative Regulation Of Collagen Biosynthetic Process Response To Interferon-gamma Positive Regulation Of MHC Class I Biosynthetic Process Positive Regulation Of MHC Class II Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Antibiotic Interferon-gamma-mediated Signaling Pathway	Chromatin Organization Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Cellular Response To DNA Damage Stimulus Gene Expression Viral Process Positive Regulation Of Cell Growth Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Apoptotic Process Histone H3 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Stabilization Positive Regulation Of Response To Cytokine Stimulus Response To Interleukin-1 Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Chromatin organization HIV Infection HATs acetylate histones RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation Chromatin modifying enzymes RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Ulcerative colitis ( 20228799)
Protein-Protein Interactions		17 interactors: CDK1 GSK3B GTF2B HDAC1 HDAC4 HDAC5 KAT2B NCOA1 NFYB PRKACA RFX5 RFXANK SMARCA4 TAF6 TAF9 XPO1 ZXDC	53 interactors: AHR ALL1 ANK2 APP CEBPB CIITA COIL DRAP1 EEF1A1 ELF3 FBL FBLN1 FEZ1 GALNT6 GTF2B HCFC1 HIST3H3 HNF4A HSF1 KLF6 KMT2A KPNA1 KPNA6 LAMTOR5 MYC NCOA2 NCOR1 NDRG1 NFATC2 NR1D2 NUFIP1 RBM48 RELA RNF138 RPS14 RPS24 RUVBL1 RUVBL2 SF3B3 TAF1 TAF10 TAF11 TAF12 TAF2 TAF4 TAF5 TAF6 TAF6L TAF7 TAF8 TBCA TP53 UBA1
Entrez ID		4261	6880
HPRD ID		02475	15983
Ensembl ID		ENSG00000179583	ENSG00000085231
Uniprot IDs		E9PFE0 P33076 Q66X48	Q16594
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Biosynthetic Process Histone Modification Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Gene Expression Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of RNA Metabolic Process Chromatin Modification Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Organization Positive Regulation Of Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-K9 Modification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Peptidyl-amino Acid Modification Chromatin Remodeling Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Initiation Histone H4 Deacetylation Regulation Of Protein Export From Nucleus Peptidyl-lysine Modification Regulation Of Binding Histone Acetylation Transcription From RNA Polymerase II Promoter Internal Peptidyl-lysine Acetylation Viral Process Peptidyl-lysine Acetylation Negative Regulation Of Biosynthetic Process Internal Protein Amino Acid Acetylation Response To Organic Substance	RNA Metabolic Process RNA Biosynthetic Process Gene Expression Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Histone Acetylation Biosynthetic Process Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Transcription Elongation From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Metabolic Process Cellular Metabolic Process Peptidyl-lysine Modification Chromatin Organization Chromatin Modification Histone Modification Chromosome Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process
Tagcloud ?		absent additionally allograft assayed class constitutively derepression fetal gamma histocompatibility ifn inducer lesion mhc neither preventing problem promoters rejection rfx suppression transactivator transfected transfection trophoblast trophoblasts vector x2bp	acetyltransferase associates box coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap
Tagcloud (Difference) ?		absent additionally allograft assayed class constitutively derepression fetal gamma histocompatibility ifn inducer lesion mhc neither preventing problem promoters rejection rfx suppression transactivator transfected transfection trophoblast trophoblasts vector x2bp	acetyltransferase associates box coactivators contacted crosslinking dimerization gcn5 hat hence homology interacting m2 m3 macromolecular max mbi moderately motifs myc partner spt3 staga sub substitutions tad tert transactivation trrap
Tagcloud (Intersection) ?