MEOX1 and PPM1F

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MEOX1	PPM1F
Description		mesenchyme homeobox 1	protein phosphatase, Mg2+/Mn2+ dependent 1F
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleus Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	Phosphoprotein Phosphatase Activity Protein Serine/threonine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Hydrolase Activity Calmodulin-dependent Protein Phosphatase Activity Cation Binding Metal Ion Binding
	Biological Process	Somite Specification Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Apoptotic Process Signal Transduction Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell Migration Regulation Of Protein Localization Intracellular Signal Transduction Negative Regulation Of DNA-templated Transcription Positive Regulation Of Growth Positive Regulation Of Chemotaxis Negative Regulation Of Protein Transport Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Cellular Response To Xenobiotic Stimulus Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways			Negative regulation of NMDA receptor-mediated neuronal transmission
Drugs
Diseases
GWAS		Fractures ( 30158200)	Adventurousness ( 30643258) Attention deficit hyperactivity disorder ( 18839057) Bipolar disorder ( 31043756)
Interacting Genes		99 interacting genes: ACBD4 ACOT12 AIRIM ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf50 CACNB3 CATSPERT CCDC102B CDC34 CIAO1 CIB3 CIMIP4 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DNAAF19 DUSP3 EIF4A3 EIF4EBP1 EMD FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 HYCC2 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410	21 interacting genes: AATK ARHGEF7 CAMK2A ERBB2 ERBB3 ERBB4 FAM161A FEM1A FEM1B KLHL8 LATS1 LMTK2 MARS1 MEOX1 OGT PAK1 PRKAA1 PTK7 ROR1 ROR2 WEE2-AS1
Entrez ID		4222	9647
HPRD ID		02537	10163
Ensembl ID		ENSG00000005102	ENSG00000100034
Uniprot IDs		P50221	B5MCT7 P49593
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Cytosol Nucleoplasm Cytoplasm Growth Cone Filopodium Spindle Pole Centrosome Translation Repressor Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Identical Protein Binding Perinuclear Region Of Cytoplasm Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Translation At Postsynapse	Protein Kinase Activity Kinase Activity ATP Binding Nucleotide Binding Transferase Activity Transmembrane Receptor Protein Tyrosine Kinase Activity Protein Tyrosine Kinase Activity Coreceptor Activity Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ERBB3:ERBB2 Complex Wound Healing ERBB2 Signaling Pathway Protein Serine Kinase Activity Receptor Complex Neuregulin Receptor Activity Positive Regulation Of Signal Transduction Protein Serine/threonine Kinase Activity Protein Modification Process Enzyme-linked Receptor Protein Signaling Pathway ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Response To Epidermal Growth Factor Regulation Of Catalytic Activity Protein Phosphorylation Cell Surface Receptor Signaling Pathway ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Mesenchyme Development Epidermal Growth Factor Receptor Signaling Pathway Apoptotic Process Glial Cell Development Regulation Of Protein Localization Basal Plasma Membrane Phosphorylation Cell Death Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Via The C-end Degron Rule Pathway Regulation Of Insulin Receptor Signaling Pathway Axon Response To Wounding ERBB Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Fibroblast Migration Regulation Of Organ Growth
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