MEOX1 and PAX1

Number of citations of the paper that reports this interaction (PMID 11423130)
6

Data Source:
BioGRID (two hybrid, pull down)
HPRD (in vitro, two hybrid)

		MEOX1	PAX1
Gene Name		mesenchyme homeobox 1	paired box 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Molecular_function Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding	DNA Binding
	Biological Process	Somite Specification Transcription, DNA-templated Multicellular Organismal Development Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Skeletal System Development Somitogenesis Transcription From RNA Polymerase II Promoter Cell Proliferation CD4-positive, Alpha-beta T Cell Differentiation CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Parathyroid Gland Development Bone Morphogenesis Sclerotome Development
Pathways
Drugs
Diseases
GWAS			Male-pattern baldness ( 22693459 18849991 18849994)
Protein-Protein Interactions		28 interactors: ALOX5 APP APPL1 CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 MAPK9 MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PARK2 PAX1 PAX3 QRICH1 RANBP3 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	2 interactors: MEOX1 MEOX2
Entrez ID		4222	5075
HPRD ID		02537	01332
Ensembl ID		ENSG00000005102
Uniprot IDs		P50221	P15863
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Proliferation Central Nervous System Development Developmental Cell Growth Developmental Growth Developmental Growth Involved In Morphogenesis Cell Growth Protein K48-linked Ubiquitination Protein Monoubiquitination Axon Extension Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Neural Crest Cell Migration Mesenchyme Development Growth Cellular Macromolecule Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Nervous System Development Regulation Of Phosphorylation Base-excision Repair Neuron Projection Extension Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination N-acetylmannosamine Metabolic Process Positive Regulation Of Transcription, DNA-templated Developmental Pigmentation Neural Crest Cell Development Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Protein Localization To Mitochondrion Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Depurination Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Neural Crest Cell Differentiation Cognition Positive Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process	Somite Specification Segment Specification Somitogenesis Embryonic Pattern Specification Somite Development Segmentation Anterior/posterior Pattern Specification Sclerotome Development Pattern Specification Process Hematopoietic Stem Cell Differentiation Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Epithelium Development Embryo Development Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Tissue Development Neuron Death Regulation Of Transcription From RNA Polymerase II Promoter Palate Development Transcription, DNA-templated RNA Biosynthetic Process Anatomical Structure Morphogenesis Skeletal Muscle Tissue Development Positive Regulation Of Cellular Metabolic Process Skeletal Muscle Organ Development Hematopoietic Progenitor Cell Differentiation Organ Development Limb Development Mesenchyme Development RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Muscle Organ Development Macromolecule Biosynthetic Process Stem Cell Differentiation Blood Circulation Striated Muscle Tissue Development Angiogenesis Muscle Tissue Development
Tagcloud ?			abilities biopsy cervical cin3 colposcopy cytological cytology detecting diagnoses directed fifteen intraepithelial lsil lsils methylated multicenter neoplasias operating ptprr receiver scrapings sensitivities sox1 specificities standardized swabs testing triage znf582
Tagcloud (Difference) ?			abilities biopsy cervical cin3 colposcopy cytological cytology detecting diagnoses directed fifteen intraepithelial lsil lsils methylated multicenter neoplasias operating ptprr receiver scrapings sensitivities sox1 specificities standardized swabs testing triage znf582
Tagcloud (Intersection) ?