MEOX1 and PAX1

Number of citations of the paper that reports this interaction (PubMedID 11423130)
0

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vitro)

		MEOX1	PAX1
Description		mesenchyme homeobox 1	paired box 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Somite Specification Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Skeletal System Development Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Embryo Development Ending In Birth Or Egg Hatching
Pathways
Drugs
Diseases
GWAS		Fractures ( 30158200)	Adolescent idiopathic scoliosis ( 31417091 25784220 30395268 28334814) Chronotype ( 30696823) Facial morphology ( 31763980) facial morphology traits (multivariate analysis) ( 27193062) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) HDL cholesterol levels ( 32203549) Height ( 31562340) Lumbar spine bone mineral density (integral) ( 27476799) Male-pattern baldness ( 28196072 29146897 27182965 22693459 18849994 18849991) Metabolite levels ( 23823483) Monobrow ( 27182965) Sulfasalazine-induced agranulocytosis ( 28762467)
Interacting Genes		99 interacting genes: ACBD4 ACOT12 AIRIM ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf50 CACNB3 CATSPERT CCDC102B CDC34 CIAO1 CIB3 CIMIP4 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DNAAF19 DUSP3 EIF4A3 EIF4EBP1 EMD FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 HYCC2 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410	2 interacting genes: MEOX1 MEOX2
Entrez ID		4222	5075
HPRD ID		02537	01332
Ensembl ID		ENSG00000005102	ENSG00000125813
Uniprot IDs		P50221	A0A087WXV5 P15863
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Cytosol Nucleoplasm Cytoplasm Growth Cone Filopodium Spindle Pole Centrosome Translation Repressor Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Identical Protein Binding Perinuclear Region Of Cytoplasm Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Translation At Postsynapse	Somite Specification Segment Specification Somite Development Embryonic Pattern Specification Epithelium Development Sclerotome Development Pattern Specification Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity HMG Box Domain Binding Tissue Development Hematopoietic Stem Cell Differentiation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration Mesenchyme Development Skeletal Muscle Tissue Development Negative Regulation Of Endothelial Cell Migration Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Roof Of Mouth Development Positive Regulation Of RNA Metabolic Process Hematopoietic Progenitor Cell Differentiation Stem Cell Differentiation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration DNA Binding Striated Muscle Tissue Development Muscle Tissue Development Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Endothelial Cell Migration Positive Regulation Of Biosynthetic Process
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