MEOX1 and CIAO1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MEOX1	CIAO1
Gene Name		mesenchyme homeobox 1	cytosolic iron-sulfur assembly component 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	MMXD Complex CIA Complex
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Molecular_function Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding
	Biological Process	Somite Specification Transcription, DNA-templated Multicellular Organismal Development Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Regulation Of Transcription From RNA Polymerase II Promoter Chromosome Segregation Positive Regulation Of Cell Proliferation Iron-sulfur Cluster Assembly Small Molecule Metabolic Process
Pathways			Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: ALOX5 APP APPL1 CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 MAPK9 MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PARK2 PAX1 PAX3 QRICH1 RANBP3 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	8 interactors: APP FAM96A FAM96B GOLM1 MEOX1 SF1 SRPK1 WT1
Entrez ID		4222	9391
HPRD ID		02537	16057
Ensembl ID		ENSG00000005102
Uniprot IDs		P50221	O76071
PDB IDs			3FM0
Enriched GO Terms of Interacting Partners?		Cell Proliferation Central Nervous System Development Developmental Cell Growth Developmental Growth Developmental Growth Involved In Morphogenesis Cell Growth Protein K48-linked Ubiquitination Protein Monoubiquitination Axon Extension Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Neural Crest Cell Migration Mesenchyme Development Growth Cellular Macromolecule Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Nervous System Development Regulation Of Phosphorylation Base-excision Repair Neuron Projection Extension Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination N-acetylmannosamine Metabolic Process Positive Regulation Of Transcription, DNA-templated Developmental Pigmentation Neural Crest Cell Development Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Protein Localization To Mitochondrion Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Depurination Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Neural Crest Cell Differentiation Cognition Positive Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process	Negative Regulation Of Female Gonad Development Positive Regulation Of Male Gonad Development Regulation Of Female Gonad Development RNA Processing Sex Determination Iron-sulfur Cluster Assembly Chromosome Segregation Adrenal Gland Development RNA Splicing Positive Regulation Of Transcription From RNA Polymerase II Promoter Reproduction MRNA Processing Negative Regulation Of Metanephric Glomerular Mesangial Cell Proliferation Embryonic Pattern Specification Reproductive Process Positive Regulation Of Transcription, DNA-templated MRNA Metabolic Process Positive Regulation Of Metanephric Ureteric Bud Development Thorax And Anterior Abdomen Determination Visceral Serous Pericardium Development Synaptic Growth At Neuromuscular Junction Posterior Mesonephric Tubule Development Adrenal Cortex Formation Segmentation Nucleus Organization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Glomerulus Development Collateral Sprouting In Absence Of Injury Negative Regulation Of Glomerular Mesangial Cell Proliferation Male Gonad Development Positive Regulation Of Cellular Biosynthetic Process Primary Sex Determination Zygotic Determination Of Anterior/posterior Axis, Embryo Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Sclerotome Development Developmental Process Involved In Reproduction Collateral Sprouting Axon Midline Choice Point Recognition MRNA 3'-splice Site Recognition Negative Regulation Of Cell Proliferation Involved In Kidney Development Male Sex Differentiation RNA Metabolic Process Sexual Reproduction Regulation Of Transcription From RNA Polymerase II Promoter Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Somite Specification Cardiac Muscle Cell Fate Commitment Intracellular Receptor Signaling Pathway Multicellular Organismal Reproductive Process
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