MEOX1 and TXNL4B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MEOX1	TXNL4B
Description		mesenchyme homeobox 1	thioredoxin like 4B
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Cytosol U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding HMG Box Domain Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Somite Specification Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS		Fractures ( 30158200)	Apolipoprotein B levels ( 32203549) Coronary artery disease ( 29212778) Hematocrit ( 32888494) Hemoglobin ( 32888494) LDL cholesterol levels ( 32203549) Lipoprotein (a) levels ( 33730874) Low density lipoprotein cholesterol levels ( 30718733 32154731) Medication use (HMG CoA reductase inhibitors) ( 31015401) Red blood cell count ( 32888494) Total cholesterol levels ( 30718733) Triglyceride levels ( 32154731 32203549)
Interacting Genes		99 interacting genes: ACBD4 ACOT12 AIRIM ALOX5 ANAPC2 APP APPL1 ATG9A BANP BNIP2 BYSL C14orf119 C1orf50 CACNB3 CATSPERT CCDC102B CDC34 CIAO1 CIB3 CIMIP4 CKS1B CNOT11 CSNK2A1 CWF19L2 CYFIP1 DCX DNAAF19 DUSP3 EIF4A3 EIF4EBP1 EMD FMR1 GCC1 GEMIN2 GPANK1 GYS1 HMBOX1 HMGB3 HOMER3 HOXC8 HYCC2 INPP5J KANK2 KCTD7 L3MBTL2 LMNA MAPK9 MBD3 MCRS1 MEF2A MID1 MID2 MKRN3 MLX MORF4L1 MVP NAGK NDOR1 NEIL2 OSGIN1 PAGE3 PARVG PAX1 PAX3 PCP2 PDE4C PELI2 PIN1 PLCD4 PM20D2 POLR3GL PPM1F PRKAG1 PRKN QRICH1 RAD52 RANBP3 RBM41 RBM5 SDCBP SEC14L4 SOX10 SPAG8 SPIC SYT17 TCEANC TCP11L1 TRAPPC2L TRIM41 TRIML2 TRIP10 TXLNA TXNL4B UBE2R2 UBXN2B UBXN7 UNC45A ZCCHC10 ZNF410	13 interacting genes: AIPL1 ALKBH4 BHLHE40 MEOX1 MEOX2 PICK1 PLEKHF2 PNMA5 PRPF6 REL SF1 SPG21 TCF4
Entrez ID		4222	54957
HPRD ID		02537	11655
Ensembl ID		ENSG00000005102	ENSG00000140830
Uniprot IDs		P50221	Q9NX01
PDB IDs			1XBS 3GIX 4IN0 8Y6O
Enriched GO Terms of Interacting Partners?		Protein Binding Cytosol Nucleoplasm Cytoplasm Growth Cone Filopodium Spindle Pole Centrosome Translation Repressor Activity Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Identical Protein Binding Perinuclear Region Of Cytoplasm Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Translation At Postsynapse	Somite Specification Segment Specification Somite Development DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific Double-stranded DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Limb Development E-box Binding Spliceosomal Complex Assembly Farnesylated Protein Binding DNA N6-methyladenine Demethylase Activity Embryonic Pattern Specification Cleavage Furrow Ingression Positive Regulation Of Transcription By RNA Polymerase II Sclerotome Development Beta-catenin-TCF7L2 Complex Protein Farnesylation
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