MEOX1 and UBXN2B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MEOX1	UBXN2B
Gene Name		mesenchyme homeobox 1	UBX domain protein 2B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus Endoplasmic Reticulum Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Core Promoter Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Molecular_function Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding HMG Box Domain Binding	Protein Phosphatase Type 1 Regulator Activity Ubiquitin Binding
	Biological Process	Somite Specification Transcription, DNA-templated Multicellular Organismal Development Biological_process Positive Regulation Of Transcription From RNA Polymerase II Promoter Hematopoietic Stem Cell Differentiation Somite Development Sclerotome Development	Autophagic Vacuole Assembly Golgi Organization Nuclear Envelope Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Catalytic Activity Membrane Fusion
Pathways
Drugs
Diseases
GWAS			Narcolepsy with cataplexy ( 23496005)
Protein-Protein Interactions		28 interactors: ALOX5 APP APPL1 CIAO1 CIB3 CKS1B CWF19L2 CYFIP1 DCX FMR1 MAPK9 MID1 MORF4L1 MVP NAGK NEIL2 PAGE3 PARK2 PAX1 PAX3 QRICH1 RANBP3 SOX10 SYT17 TCEANC TXLNA UBE2R2 UBXN2B	6 interactors: CRX INCA1 MEOX1 NGLY1 VAT1L VCP
Entrez ID		4222	137886
HPRD ID		02537	18973
Ensembl ID		ENSG00000005102	ENSG00000215114
Uniprot IDs		P50221	E5RJ36 Q14CS0
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Proliferation Central Nervous System Development Developmental Cell Growth Developmental Growth Developmental Growth Involved In Morphogenesis Cell Growth Protein K48-linked Ubiquitination Protein Monoubiquitination Axon Extension Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Neural Crest Cell Migration Mesenchyme Development Growth Cellular Macromolecule Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Nervous System Development Regulation Of Phosphorylation Base-excision Repair Neuron Projection Extension Synaptic Growth At Neuromuscular Junction Positive Regulation Of Protein Linear Polyubiquitination N-acetylmannosamine Metabolic Process Positive Regulation Of Transcription, DNA-templated Developmental Pigmentation Neural Crest Cell Development Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Proteasomal Protein Catabolic Process Protein Localization To Mitochondrion Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine Depurination Dopamine Uptake Involved In Synaptic Transmission Collateral Sprouting In Absence Of Injury Neural Crest Cell Differentiation Cognition Positive Regulation Of Proteolysis Regulation Of Phosphorus Metabolic Process	Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Positive Regulation Of Photoreceptor Cell Differentiation Sclerotome Development Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Deubiquitination Somite Specification Protein Hexamerization Aggresome Assembly Translesion Synthesis Glycoprotein Catabolic Process Hematopoietic Stem Cell Differentiation
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