CIAO1 and SHISA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CIAO1	SHISA6
Description		cytosolic iron-sulfur assembly component 1	shisa family member 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm MMXD Complex Cytosolic [4Fe-4S] Assembly Targeting Complex	Postsynaptic Density Membrane AMPA Glutamate Receptor Complex Dendritic Spine Membrane Synapse Postsynaptic Membrane Postsynaptic Density Membrane Glutamatergic Synapse Asymmetric, Glutamatergic, Excitatory Synapse
	Molecular Function	Protein Binding	Protein Binding PDZ Domain Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation	Spermatogenesis Wnt Signaling Pathway Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Canonical Wnt Signaling Pathway Postsynaptic Neurotransmitter Receptor Diffusion Trapping Excitatory Chemical Synaptic Transmission Regulation Of AMPA Glutamate Receptor Clustering
Pathways		Cytosolic iron-sulfur cluster assembly
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Copper levels ( 26025379) Daytime sleep phenotypes ( 27126917) Myopia ( 27182965) Obesity-related traits ( 23251661) Refractive error ( 23396134 32231278) Seborrheic dermatitis ( 29203360) Sleep duration (short sleep) ( 30846698) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Waist-hip ratio ( 28552196) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		16 interacting genes: CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B UBC WT1	29 interacting genes: ANKS1A ARMC7 BAG3 CARD9 CCDC57 CDKN1A CIAO1 CTBP2 CYSRT1 EXOSC5 FBLIM1 GOLGA2 HSF2BP KAT5 KIF9 KIFC3 KRT31 KRTAP3-3 LMO3 NEDD4 OIP5 PFDN5 PLEKHG4 SMARCD1 TLE5 TRIP6 TSSK3 TTC19 UBASH3A
Entrez ID		9391	388336
HPRD ID		16057	13507
Ensembl ID		ENSG00000144021	ENSG00000188803
Uniprot IDs		O76071	Q6ZSJ9
PDB IDs		3FM0
Enriched GO Terms of Interacting Partners?		Somite Specification Chromosome Segregation Cytosolic [4Fe-4S] Assembly Targeting Complex Segment Specification Somite Development	Positive Regulation Of Aggrephagy
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