CIAO1 and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 37689310)
63

Data Source:
BioGRID (two hybrid, proximity labelling technology)

		CIAO1	PGRMC1
Description		cytosolic iron-sulfur assembly component 1	progesterone receptor membrane component 1
Image
GO Annotations	Cellular Component	Cytoplasm MMXD Complex Cytosolic [4Fe-4S] Assembly Targeting Complex	Extracellular Region Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Lipid Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Chromosome Segregation Iron-sulfur Cluster Assembly Protein Maturation	Heme Biosynthetic Process Axon Guidance Memory Associative Learning Modification Of Synaptic Structure Positive Regulation Of Lipoprotein Transport Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Synapse Organization
Pathways		Cytosolic iron-sulfur cluster assembly	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS			Hodgkin's lymphoma ( 34216518)
Interacting Genes		16 interacting genes: CCDC7 CIAO2A CIAO2B GOLM1 HAUS3 MEOX1 MEOX2 PGRMC1 RGS2 SHISA6 SLC4A7 SRPK1 TCP10L TOP3B UBC WT1	20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A PAM16 SCAP SGTB TMEM213 ZNF71
Entrez ID		9391	10857
HPRD ID		16057	02338
Ensembl ID		ENSG00000144021	ENSG00000101856
Uniprot IDs		O76071	O00264 Q6IB11
PDB IDs		3FM0	4X8Y
Enriched GO Terms of Interacting Partners?		Somite Specification Chromosome Segregation Cytosolic [4Fe-4S] Assembly Targeting Complex Segment Specification Somite Development	GET Complex
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