SNRPB2 and ZBTB14

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		SNRPB2	ZBTB14
Description		small nuclear ribonucleoprotein polypeptide B2	zinc finger and BTB domain containing 14
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Spliceosomal Complex U2-type Spliceosomal Complex U1 SnRNP U2 SnRNP Nuclear Speck Cytoplasmic Ribonucleoprotein Granule U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Spliceosomal SnRNP Complex Ribonucleoprotein Complex	Nucleus Nucleoplasm Nucleolus Cytosol Aggresome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding U1 SnRNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing U2-type Prespliceosome Assembly	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Kidney Development Regulation Of Immune System Process Heart Valve Development Cardiac Septum Development Negative Regulation Of DNA-templated Transcription Coronary Vasculature Development
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Food allergy (maternal genetic effects) ( 29489655) Metabolite levels ( 23823483) Response to haloperidol in schizophrenia ( 29503163)	Cerebral amyloid deposition (PET imaging) ( 26252872) Lacunar stroke ( 33773637)
Interacting Genes		26 interacting genes: ALAS1 CALM1 CEBPA CMTM6 DHX9 ERBB3 FOXP1 GABPB1 GABPB2 GOLGA2 HMBOX1 HNRNPUL1 HOMEZ HTATSF1 MCM6 MTUS2 NAP1L5 PICK1 PNMA1 PTEN SMN2 SNRPA1 SUGP1 TRIM23 TRIM27 ZBTB14	51 interacting genes: AP1M1 ATP5PO ATRIP BAZ2B BYSL C2orf68 CAPN6 CBX8 CDK16 CDKL3 CEP19 DDX6 EAF1 EIF1AD ENKD1 EPM2AIP1 FAM161A FAM90A1 GORASP2 INTS3 KAT5 MAD2L1BP MFAP1 MORF4L2 MRPL11 NAA10 NAA11 OGT PIN1 PNKP POLR2L PRMT1 RNASEH2B RNPS1 RPA1 RPA2 RPL9 RPS25 RPS7 SCNM1 SDCBP SNRPB2 SYT16 TCEANC TRIM55 TSTD2 TXN2 WNT9A ZBTB21 ZCCHC10 ZMAT2
Entrez ID		6629	7541
HPRD ID		04628	03674
Ensembl ID		ENSG00000125870	ENSG00000198081
Uniprot IDs		P08579	B2R850 O43829
PDB IDs		1A9N 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF7 6ICZ 6ID0 6ID1 6QDV 6QX9 6Y53 6Y5Q 7A5P 7ABG 7ABI 7EVO 7VPX 7W59 7W5A 7W5B 8C6J 8CH6 8H6E 8H6J 8H6K 8H6L 8HK1 8I0P 8I0R 8I0S 8I0T 8I0U 8I0V 8I0W 8QO9 8QXD 8QZS 8R08 8R09 8R0A 8R0B 8RM5 9FMD
Enriched GO Terms of Interacting Partners?		Identical Protein Binding Nucleoplasm Nucleus RNA Splicing RNA Splicing, Via Transesterification Reactions Single-stranded 3'-5' DNA Helicase Activity RISC Complex Binding MRNA Metabolic Process CRD-mediated MRNA Stability Complex MRNA Processing Spliceosomal Complex Assembly Importin-alpha Family Protein Binding CRD-mediated MRNA Stabilization Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay RNA Stem-loop Binding Cytoplasmic Ribonucleoprotein Granule Protein-RNA Complex Assembly MRNA Splicing, Via Spliceosome Meiotic Spindle Assembly Positive Regulation Of Cytoplasmic Translation DNA-templated Transcription Termination Regulation Of Viral Transcription Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Meiotic Spindle Organization Macromolecule Metabolic Process Transcription Cis-regulatory Region Binding Nucleic Acid Metabolic Process Alternative MRNA Splicing, Via Spliceosome PML Body U2-type Prespliceosome Assembly U2 SnRNP U2-type Spliceosomal Complex RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Dendritic Spine Organization Response To Stress Protein Binding Positive Regulation Of Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding 3'-5' DNA/RNA Helicase Activity Regulation Of Cytoplasmic Translation DNA-templated Viral Transcription Regulatory Region RNA Binding Negative Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Organ Growth Regulation Of Actin Nucleation Telomere-telomerase Complex Assembly DNA Helicase Activity RNA Processing Nucleic Acid Binding	Nucleoplasm Nucleus Macromolecule Metabolic Process Nucleic Acid Metabolic Process Regulation Of Double-strand Break Repair Regulation Of DNA Repair Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Site Of Double-strand Break Protein N-terminal-serine Acetyltransferase Activity Nucleotide-excision Repair Protein Binding DNA Repair Regulation Of Cell Cycle Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Response To Stress Recombinational Repair Positive Regulation Of DNA Repair Double-strand Break Repair Double-strand Break Repair Via Homologous Recombination Mismatch Repair NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Protein Acetylation Positive Regulation Of Double-strand Break Repair Positive Regulation Of Mitotic Sister Chromatid Segregation Positive Regulation Of Double-strand Break Repair Via Homologous Recombination G-rich Strand Telomeric DNA Binding RNA Processing MRNA Splicing, Via Spliceosome U2-type Precatalytic Spliceosome N-terminal Protein Amino Acid Acetylation Clathrin Adaptor Complex Organelle Assembly RNA Splicing, Via Transesterification Reactions DNA Replication Factor A Complex Cytoplasmic Translation RNA Metabolic Process DNA Metabolic Process Regulation Of Cell Cycle Process
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