CBFA2T3 and RUNX1T1

Number of citations of the paper that reports this interaction (PMID 14703694)
5

Data Source:
HPRD (in vivo)

		CBFA2T3	RUNX1T1
Gene Name		core-binding factor, runt domain, alpha subunit 2; translocated to, 3	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Nucleoplasm Nucleolus	Nucleoplasm Cytoplasm Mitochondrion Nuclear Matrix
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Cell Proliferation Granulocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Generation Of Precursor Metabolites And Energy Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: CBFA2T2 GMEB2 HDAC1 HDAC3 MATN2 PRKAR2A RUNX1 RUNX1T1 SEC24A TCF3 ZBTB33 ZBTB38 ZBTB4 ZNF652	53 interactors: ABI3 ATN1 BCL6 BRCA1 C19orf57 CBFA2T3 CCDC36 CEP170P1 CPSF7 CREB3L1 DNMT1 EFHC2 EPS8 ETS1 GFI1 GSE1 HDAC1 HDAC3 HDAC8 HOMER3 HSP90AA1 ID1 ID3 KPNA1 KPNB1 LPXN LZTS2 MEOX2 MID2 NCOR1 NCOR2 NECAB2 NEUROG1 PCBD2 PRDM14 PRKAR2A SIN3A SPEN SPERT SPRY2 STX11 TAF9B TAL2 TCF12 TCF3 TCF4 TRIM42 UBQLN4 VDR WBP11 ZBTB16 ZMYM4 ZNF652
Entrez ID		863	862
HPRD ID		04847	00590
Ensembl ID		ENSG00000129993	ENSG00000079102
Uniprot IDs		O75081	B2R6I9 Q06455
PDB IDs			1WQ6 2DJ8 2H7B 2KNH 2KYG 2OD1 2ODD 2PP4 4JOL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transcription, DNA-templated Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Gene Expression Regulation Of Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Receptor Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Histone H4 Deacetylation Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Histone H3 Deacetylation Histone H3-K9 Modification Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Skin Development Response To Growth Factor Dendrite Regeneration Histone Deacetylation Protein Deacetylation Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process Circadian Regulation Of Gene Expression Positive Regulation Of Progesterone Secretion Cellular Metabolic Process	Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Negative Regulation Of Gene Expression Cellular Aromatic Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Cellular Process Multicellular Organismal Development Positive Regulation Of Macromolecule Biosynthetic Process Response To Organic Substance Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Embryo Development Cellular Metabolic Process Organ Development Developmental Process Anatomical Structure Development System Development Transcription Initiation From RNA Polymerase II Promoter Regulation Of Cell Differentiation Cellular Response To Organic Substance Rhythmic Process Organelle Organization Regulation Of Apoptotic Process
Tagcloud ?		7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned recurrently silent smzl spen splenic tnfaip3 trrap ush2a wes	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 precise ptd recurrently registered sole stratified translocations
Tagcloud (Difference) ?		7q amotl1 cn crebbp cul1 directory exome expanding expands fat4 fbxo11 flnc ighv1 integrating map3k14 minimally mll2 notch2 pla2g4d positioned silent smzl spen splenic tnfaip3 trrap ush2a wes	accumulated aml aml201 cbfb cebpa chimeric clarify comprehensively cooperative cytogenetically cytogenetics dnmt3a exclusive flt3 impacts japan kit leukemianet mll myh11 npm1 precise ptd registered sole stratified translocations
Tagcloud (Intersection) ?		recurrently