SMIM3 and CNIH1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMIM3	CNIH1
Description		small integral membrane protein 3	cornichon family member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus ER To Golgi Transport Vesicle Membrane Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process		Immune Response Signal Transduction Vesicle-mediated Transport
Pathways			COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Monobrow thickness ( 26926045)
Interacting Genes		52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1	32 interacting genes: AQP6 BIK CD53 CD79A CLDN7 CPLX4 CYB5R3 ERGIC3 EVI2B FAM209A FCER1G FFAR2 FKBP7 GPR152 GPX8 HTR2C LEUTX LRRC59 MCEMP1 MFF MRM1 OPRM1 RNF24 SAR1A SHISA4 SLC10A6 SLC18A1 SLC22A23 SLC35H1 SMIM3 TMEM52B TSC1
Entrez ID		85027	10175
HPRD ID		12212	16730
Ensembl ID		ENSG00000256235	ENSG00000100528
Uniprot IDs		Q9BZL3	B2R4P1 O95406
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Bleb Assembly Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Endoplasmic Reticulum Membrane Sarcoglycan Complex Fucose Binding Myelination Pattern Recognition Receptor Activity Bicellular Tight Junction Assembly Protein Binding Structural Constituent Of Myelin Sheath Schmidt-Lanterman Incisure Tight Junction Assembly Bicellular Tight Junction Central Nervous System Myelination Tight Junction Organization	Membrane
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