SMIM3 and BSCL2

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		SMIM3	BSCL2
Gene Name		small integral membrane protein 3	Berardinelli-Seip congenital lipodystrophy 2 (seipin)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function		Molecular_function
	Biological Process		Lipid Catabolic Process Lipid Storage Lipid Particle Organization Fat Cell Differentiation Negative Regulation Of Lipid Catabolic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1	6 interactors: NSG1 PLEKHF2 SMIM3 SMLR1 TMEM19 USE1
Entrez ID		85027	26580
HPRD ID		12212	05858
Ensembl ID		ENSG00000256235	ENSG00000168000
Uniprot IDs		Q9BZL3	Q96G97
PDB IDs
Enriched GO Terms of Interacting Partners?		Bleb Assembly Inflammatory Response Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Carbohydrate Mediated Signaling Membrane Raft Polarization Activation Of Innate Immune Response Myelination Axon Ensheathment Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Membrane Raft Localization Positive Regulation Of Innate Immune Response Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Regulation Of Innate Immune Response Positive Regulation Of Protein Homodimerization Activity Spindle Midzone Assembly 3'-UTR-mediated MRNA Stabilization Cellular Response To Bacterial Lipopeptide T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Cell Projection Assembly Cell Death Death Regulation Of Wnt Signaling Pathway Positive Regulation Of Toll-like Receptor Signaling Pathway Microtubule Severing Lipid Particle Organization Leukocyte Cell-cell Adhesion Cellular Response To Lipoteichoic Acid Positive Regulation Of Interleukin-6 Biosynthetic Process Homotypic Cell-cell Adhesion Positive Regulation Of Transcription Via Serum Response Element Binding Apical Protein Localization Phagocytosis, Recognition Negative Regulation Of Lipid Catabolic Process Regulation Of Protein Homodimerization Activity Membrane Raft Organization Immune Response Regulation Of Interleukin-6 Biosynthetic Process Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Lymphocyte Activation Defense Response To Protozoan	Endoplasmic Reticulum Tubular Network Organization Regulation Of ER To Golgi Vesicle-mediated Transport Clathrin Coat Assembly Dopamine Receptor Signaling Pathway Lysosomal Transport Endoplasmic Reticulum Organization Transport Membrane Budding Vacuolar Transport Protein Transport Establishment Of Protein Localization
Tagcloud ?			adipocyte adipogenesis adipose autonomous berardinelli bring cgl cgls congenital contributions cytoskeletal depots droplet handful ld lipin lipodystrophic lipodystrophy localizes mechanistically partners recapitulate remodelling scaffolding seip seipin storage termini truncations
Tagcloud (Difference) ?			adipocyte adipogenesis adipose autonomous berardinelli bring cgl cgls congenital contributions cytoskeletal depots droplet handful ld lipin lipodystrophic lipodystrophy localizes mechanistically partners recapitulate remodelling scaffolding seip seipin storage termini truncations
Tagcloud (Intersection) ?