SMIM3 and RPRM

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMIM3	RPRM
Description		small integral membrane protein 3	reprimo, TP53 dependent G2 arrest mediator homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cytoplasm Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process		Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS		Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)	Anti-saccade response ( 29064472) Blood trace element (Zn levels) ( 23720494) Heel bone mineral density ( 30598549) Lung cancer ( 28604730) Recurrent major depressive disorder x sex interaction ( 34099189)
Interacting Genes		52 interacting genes: ASGR2 ATP1B4 ATP6V0C BNIP3 BSCL2 BTNL9 CD53 CD79A CD82 CLDN11 CLDN5 CLDN8 CLEC17A CLEC7A CNIH1 CNIH3 EBP EMP1 EMP3 ERGIC3 FNDC9 GIMAP5 GPR42 IFNGR2 KIR3DL3 LPAR6 LSMEM2 LZTS2 MAL MS4A3 PDCD1LG2 PLP1 PMP22 PNMA1 PSCA RPRM SEC22A SFTPC SGCB SGCZ SLC22A1 SLC38A1 SMCO4 SPACA1 STX1A TEX264 TM4SF18 TMEM182 TMEM218 TMEM31 TRIM14 ZFPL1	80 interacting genes: ADGRG3 AMIGO1 AQP6 ARFIP1 ASGR2 BNIP3 BSCL2 BTNL9 C16orf54 CD33 CD53 CD69 CLDN5 CLDN7 CLDN9 CLEC17A CLEC2D COQ8A CREB3 CXorf66 EHHADH EMP1 FAM209A FAM210B FATE1 FBXL19 FCGR1A FFAR2 FGD2 FKBP7 FNDC9 GAD2 GJA5 GJB3 GJB5 GNG13 GPR37L1 GPR42 GPX8 HHLA2 HIP1 HSD17B13 KCNJ6 LAPTM5 LHFPL5 LMNA LPAR6 MPP1 MS4A4A MTIF3 OPRD1 OPRM1 PBX3 PDZK1IP1 PLEKHF2 PNKP SCAND1 SDCBP SENP2 SLC18A1 SLC38A1 SMIM3 SNX11 SNX12 SNX3 SPACA1 SPCS1 STOM SUSD3 SYT16 TM4SF18 TMEM106C TMEM237 TMEM79 TMEM80 TMEM86B TSPO2 TTPA WDFY2 ZDHHC22
Entrez ID		85027	56475
HPRD ID		12212	18002
Ensembl ID		ENSG00000256235	ENSG00000177519
Uniprot IDs		Q9BZL3	Q9NS64
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Plasma Membrane Bleb Assembly Axon Ensheathment Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Endoplasmic Reticulum Membrane Sarcoglycan Complex Fucose Binding Myelination Pattern Recognition Receptor Activity Bicellular Tight Junction Assembly Protein Binding Structural Constituent Of Myelin Sheath Schmidt-Lanterman Incisure Tight Junction Assembly Bicellular Tight Junction Central Nervous System Myelination Tight Junction Organization	Membrane Protein Binding Plasma Membrane Negative Regulation Of Early Endosome To Late Endosome Transport Connexin Complex Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Gap Junction Channel Activity Endoplasmic Reticulum Phosphatidylinositol Binding External Side Of Plasma Membrane Gap Junction Gamma-aminobutyric Acid Biosynthetic Process Phosphatidylinositol Phosphate Binding Late Endosome To Golgi Transport
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