LOR and KRT1

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		LOR	KRT1
Gene Name		loricrin	keratin 1, type II
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytoplasm	Extracellular Space Nucleus Cytoskeleton Plasma Membrane Membrane Extracellular Matrix Keratin Filament Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging	Receptor Activity Structural Molecule Activity Protein Binding Carbohydrate Binding
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Keratinization	Complement Activation, Lectin Pathway Retina Homeostasis Response To Oxidative Stress Fibrinolysis Regulation Of Angiogenesis Negative Regulation Of Inflammatory Response Establishment Of Skin Barrier
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM	15 interactors: CALB2 CSTA DSP EVPL F12 FANCA FANCC IVL KNG1 KRT5 LOR MBL2 PI3 PRKCE YWHAQ
Entrez ID		4014	3848
HPRD ID		01070	00763
Ensembl ID		ENSG00000203782	ENSG00000167768
Uniprot IDs		P23490	P04264
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Keratinization Epidermis Development Epithelium Development Organ Development Tissue Development System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Bergmann Glial Cell Differentiation Complement Activation, Lectin Pathway Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Response To UV-B Establishment Of Skin Barrier Regulation Of Endopeptidase Activity Intermediate Filament Organization Negative Regulation Of Hydrolase Activity Lens Fiber Cell Development Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Water Loss Via Skin Copulation Astrocyte Development Cellular Protein Modification Process Fibrinolysis Protein Metabolic Process Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Multicellular Organismal Water Homeostasis Regulation Of Proteolysis Mating Negative Regulation Of Blood Coagulation SMAD Protein Signal Transduction	Peptide Cross-linking Keratinocyte Differentiation Epidermis Development Epidermal Cell Differentiation Skin Development Keratinization Epithelial Cell Differentiation Epithelium Development Blood Coagulation, Intrinsic Pathway Regulation Of Wound Healing Regulation Of Protein Processing Protein Activation Cascade Cytosolic Calcium Ion Homeostasis Tissue Development Positive Regulation Of Wound Healing Wound Healing Negative Regulation Of Endopeptidase Activity Negative Regulation Of Blood Coagulation Negative Regulation Of Peptidase Activity Negative Regulation Of Coagulation Positive Regulation Of Cellular Glucuronidation Response To Wounding Cellular Calcium Ion Homeostasis Negative Regulation Of Wound Healing Calcium Ion Homeostasis Positive Regulation Of Transport Anatomical Structure Development Acute Inflammatory Response Organ Development Negative Regulation Of Proteolysis Ventricular Compact Myocardium Morphogenesis Factor XII Activation TRAM-dependent Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Regulation Of Blood Coagulation Negative Regulation Of Hydrolase Activity Cellular Metal Ion Homeostasis Regulation Of Peptidase Activity Blood Coagulation Inflammatory Response Developmental Process Hemostasis Protein Metabolic Process Cellular Cation Homeostasis Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Protein Localization To Adherens Junction Positive Regulation Of Fibrinolysis Cellular Ion Homeostasis Response To Stress
Tagcloud ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo	arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously
Tagcloud (Difference) ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo	arose backcrosses bareskin bsk chr clustered corneal den denuded facility granulin grn hair intersubspecific junctional jup keratin kinds linkage mapped opacity plakoglobin portion rara recombination resembling rex rim3 spontaneously
Tagcloud (Intersection) ?