LOR and IVL

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		LOR	IVL
Gene Name		loricrin	involucrin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytoplasm	Cornified Envelope Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging	Structural Molecule Activity Protein Binding, Bridging
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Keratinization	Response To UV-B Peptide Cross-linking Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Keratinocyte Differentiation Keratinization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM	9 interactors: ACD CSTA DSP EVPL KRT1 LOR POT1 SPRR3 UCHL5
Entrez ID		4014	3713
HPRD ID		01070	00931
Ensembl ID		ENSG00000203782	ENSG00000163207
Uniprot IDs		P23490	P07476
PDB IDs			1EU0
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Keratinization Epidermis Development Epithelium Development Organ Development Tissue Development System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Bergmann Glial Cell Differentiation Complement Activation, Lectin Pathway Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Response To UV-B Establishment Of Skin Barrier Regulation Of Endopeptidase Activity Intermediate Filament Organization Negative Regulation Of Hydrolase Activity Lens Fiber Cell Development Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Water Loss Via Skin Copulation Astrocyte Development Cellular Protein Modification Process Fibrinolysis Protein Metabolic Process Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Multicellular Organismal Water Homeostasis Regulation Of Proteolysis Mating Negative Regulation Of Blood Coagulation SMAD Protein Signal Transduction	Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Keratinization Epithelial Cell Differentiation Telomere Assembly Telomere Capping Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase System Development Regulation Of Telomerase Activity Organ Development Multicellular Organismal Development Epithelium Development Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Anatomical Structure Development Developmental Process Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Tissue Development Positive Regulation Of DNA Replication Telomere Maintenance Cellular Protein Modification Process Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Ventricular Compact Myocardium Morphogenesis Protein Metabolic Process Regulation Of DNA Replication Telomere Formation Via Telomerase Positive Regulation Of DNA Metabolic Process Protein Localization To Adherens Junction Protection From Non-homologous End Joining At Telomere Cellular Protein Metabolic Process Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Helicase Activity Positive Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Catalytic Activity Regulation Of Chromosome Organization Complement Activation, Lectin Pathway Bundle Of His Cell To Purkinje Myocyte Communication Protein Localization To Cell Junction Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase
Tagcloud ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo	attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl penetration permit powerful prognoses relapse rituximab sanctuary solely systemic ways
Tagcloud (Difference) ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic permeation pg propylene tween viscosity xefo	attack bleak chemotherapeutic cns deeply dehydrogenase detecting differs distinguish earnestly fdg imagery intravascular lactate lymphatic lymphoma lymphomatosis methotrexate pcnsl permit powerful prognoses relapse rituximab sanctuary solely systemic ways
Tagcloud (Intersection) ?		penetration