LORICRIN

Name	loricrin cornified envelope precursor protein
Structure	No pdb structure
Interactors	8 interactors: CSTA EVPL IVL KRT1 PI3 SLC26A4-AS1 SPRR3 VIM
GO Annotations	Cellular Component	Cornified Envelope Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Cytoskeleton Organization Peptide Cross-linking Keratinocyte Differentiation Keratinization
Pathways	Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Diseases	Vohwinkel syndrome, including: Vohwinkel syndrome (VS); Vohwinkel syndrome with ichthyosis
GWAS	No GWAS studies recorded
Entrez ID	4014
HPRD ID	01070
Ensembl ID	ENSG00000203782
Uniprot IDs	P23490
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Peptide Cross-linking Cornified Envelope Keratinocyte Differentiation Keratinization Epidermal Cell Differentiation Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Epithelial Cell Differentiation Epidermis Development Intermediate Filament Endopeptidase Inhibitor Activity Intermediate Filament Cytoskeleton Protein Modification Process Structural Constituent Of Skin Epidermis Wound Healing Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Intermediate Filament Organization Copulation Extracellular Exosome Peptidase Inhibitor Activity Peptidase Inhibitor Complex Cell Differentiation Cytosol Regulation Of Antibacterial Peptide Production Keratin Filament Binding Structural Molecule Activity Tissue Development Lens Fiber Cell Development Response To Wounding Cellular Response To Muramyl Dipeptide Bergmann Glial Cell Differentiation Cellular Developmental Process Protein Metabolic Process Regulation Of Antimicrobial Humoral Response Complement Activation, Lectin Pathway Humoral Immune Response Protein Heterotetramerization