LOR and PI3

Number of citations of the paper that reports this interaction (PMID 8999895)
22

Data Source:
BioGRID (pull down)

		LOR	PI3
Gene Name		loricrin	peptidase inhibitor 3, skin-derived
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cornified Envelope Nucleoplasm Cytoplasm	Proteinaceous Extracellular Matrix Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Protein Binding, Bridging	Endopeptidase Inhibitor Activity Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Peptide Cross-linking Keratinocyte Differentiation Keratinization	Copulation Negative Regulation Of Endopeptidase Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CSTA EVPL IVL KRT1 PI3 SPRR3 VIM	5 interactors: CELA1 CSTA EVPL KRT1 LOR
Entrez ID		4014	5266
HPRD ID		01070	15947
Ensembl ID		ENSG00000203782	ENSG00000124102
Uniprot IDs		P23490	P19957
PDB IDs			1FLE 2REL
Enriched GO Terms of Interacting Partners?		Peptide Cross-linking Skin Development Keratinocyte Differentiation Epidermal Cell Differentiation Epithelial Cell Differentiation Keratinization Epidermis Development Epithelium Development Organ Development Tissue Development System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Cell Differentiation Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Bergmann Glial Cell Differentiation Complement Activation, Lectin Pathway Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Response To UV-B Establishment Of Skin Barrier Regulation Of Endopeptidase Activity Intermediate Filament Organization Negative Regulation Of Hydrolase Activity Lens Fiber Cell Development Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Water Loss Via Skin Copulation Astrocyte Development Cellular Protein Modification Process Fibrinolysis Protein Metabolic Process Muscle Filament Sliding Actin-myosin Filament Sliding Lens Fiber Cell Differentiation Intermediate Filament Cytoskeleton Organization Astrocyte Differentiation Intermediate Filament-based Process Actin-mediated Cell Contraction Multicellular Organismal Water Homeostasis Regulation Of Proteolysis Mating Negative Regulation Of Blood Coagulation SMAD Protein Signal Transduction	Skin Development Peptide Cross-linking Keratinocyte Differentiation Epidermal Cell Differentiation Epidermis Development Organ Development Keratinization Epithelial Cell Differentiation System Development Multicellular Organismal Development Anatomical Structure Development Developmental Process Protein Metabolic Process Epithelium Development Pancreas Morphogenesis Complement Activation, Lectin Pathway Exocrine Pancreas Development Tissue Development Establishment Of Skin Barrier Regulation Of Water Loss Via Skin Fibrinolysis
Tagcloud ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo	antiapoptotic ark augmented ax1 axl cascades coincubation erk forebrain gas6 gn10 gnrh gt1 mek migrating olfactory pd98059 phosphoinositide postmigratory programmed protects rescued starved threonine tyro7 ufo windows withdrawal wortmannin
Tagcloud (Difference) ?		analgesic carbopol cyclodextrin enhancers flux formulated formulation formulations franz gel gels glycol hp hpmc hydroxylpropyl hydroxypropyl lorf3 lorf8 lornoxicam marketed methylcellulose oleic penetration permeation pg propylene tween viscosity xefo	antiapoptotic ark augmented ax1 axl cascades coincubation erk forebrain gas6 gn10 gnrh gt1 mek migrating olfactory pd98059 phosphoinositide postmigratory programmed protects rescued starved threonine tyro7 ufo windows withdrawal wortmannin
Tagcloud (Intersection) ?