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LBP and CBFA2T2
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
LBP
CBFA2T2
Gene Name
lipopolysaccharide binding protein
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cell Surface
Extracellular Vesicular Exosome
Nucleus
Molecular Function
Lipopolysaccharide Binding
Receptor Binding
Protein Binding
Lipoteichoic Acid Binding
Sequence-specific DNA Binding Transcription Factor Activity
Transcription Corepressor Activity
Protein Binding
Metal Ion Binding
Biological Process
Toll-like Receptor Signaling Pathway
Leukocyte Chemotaxis Involved In Inflammatory Response
Macrophage Activation Involved In Immune Response
Acute-phase Response
Cellular Defense Response
Opsonization
Lipopolysaccharide Transport
Lipopolysaccharide-mediated Signaling Pathway
Detection Of Molecule Of Bacterial Origin
Response To Lipopolysaccharide
Negative Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Chemokine Production
Positive Regulation Of Interleukin-6 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process
Positive Regulation Of Macrophage Activation
Negative Regulation Of Growth Of Symbiont In Host
Innate Immune Response
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Regulation Of Respiratory Burst Involved In Inflammatory Response
Cellular Response To Lipopolysaccharide
Cellular Response To Lipoteichoic Acid
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Neuron Projection Development
Negative Regulation Of Neuron Projection Development
Epithelial Cell Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Toll-Like Receptors Cascades
Toll Like Receptor 4 (TLR4) Cascade
Transfer of LPS from LBP carrier to CD14
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
19 interactors:
APOA1
BAG6
BST1
C4BPA
CAMP
CBFA2T2
CD14
CFHR1
FTH1
HSPB1
IRF6
PRDX4
PSMA3
PYCRL
RPS21
SETD1A
SMAD3
TRA2A
TSC22D4
23 interactors:
APP
ATN1
ATXN1L
CBFA2T3
CBFB
FBXL19
GTF2E1
ID3
LBP
MDFI
NCOR1
NCOR2
NEUROG1
NOTCH3
PDP1
PRDM14
RERE
RUNX1
SIN3A
TAL2
TCP1
WDYHV1
ZNF652
Entrez ID
3929
9139
HPRD ID
07175
04721
Ensembl ID
ENSG00000129988
ENSG00000078699
Uniprot IDs
P18428
Q8TCF0
O43439
PDB IDs
Enriched GO Terms of Interacting Partners
?
Immune System Process
Immune Response
Regulation Of Interleukin-1 Beta Production
Regulation Of Cell Proliferation
Humoral Immune Response
Protein Stabilization
Response To Stress
Regulation Of Protein Stability
Positive Regulation Of Interleukin-1 Beta Production
Regulation Of Protein Catabolic Process
Positive Regulation Of Interleukin-1 Production
Regulation Of Immune System Process
Posttranscriptional Regulation Of Gene Expression
Regulation Of Immune Response
Positive Regulation Of Stress Fiber Assembly
Response To Stimulus
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Actin Filament Bundle Assembly
Gene Expression
Regulation Of Cytokine Production
Positive Regulation Of Transforming Growth Factor Beta3 Production
Negative Regulation Of Male Germ Cell Proliferation
Negative Regulation Of Cell Adhesion Molecule Production
Negative Regulation Of Growth Of Symbiont On Or Near Host Surface
Regulation Of Protein Metabolic Process
Positive Regulation Of Tumor Necrosis Factor Production
I-kappaB Kinase/NF-kappaB Signaling
Cell Cycle Process
Regulation Of Stress Fiber Assembly
Regulation Of Inflammatory Response
Negative Regulation Of Cell Proliferation
Regulation Of Opsonization
Intracellular Sequestering Of Iron Ion
Negative Regulation Of Interleukin-1 Beta Secretion
Sister Chromatid Biorientation
Response To Other Organism
Positive Regulation Of Protein Metabolic Process
Epithelial Cell Proliferation
Intracellular Signal Transduction
Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling
Cholesterol Import
Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA)
Regulation Of Male Germ Cell Proliferation
Evasion Or Tolerance Of Host Defenses By Virus
Response To Biotic Stimulus
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Cytokine Production
Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Metabolic Process
Negative Regulation Of Inflammatory Response
Transcription, DNA-templated
RNA Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Nucleobase-containing Compound Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Cellular Metabolic Process
Multicellular Organismal Development
Nitrogen Compound Metabolic Process
Biosynthetic Process
Organ Development
Definitive Hemopoiesis
Central Nervous System Development
Developmental Process
System Development
Anatomical Structure Development
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Notch Signaling Pathway
Transcription From RNA Polymerase II Promoter
Negative Regulation Of Gene Expression
Cell Differentiation
Transcription Initiation From RNA Polymerase II Promoter
Negative Regulation Of Biosynthetic Process
Regulation Of Cellular Process
Negative Regulation Of Cell Differentiation
Forebrain Development
DNA-templated Transcription, Initiation
Metabolic Process
Embryo Development
Negative Regulation Of Cellular Metabolic Process
Myeloid Cell Differentiation
Thalamus Development
In Utero Embryonic Development
Nervous System Development
Positive Regulation Of Mitotic Cell Cycle
Tagcloud
?
adopt
af
agonists
allowing
apo
bms614
competent
constitutive
corepressor
der
disabled
disrupts
h11
heterodimerization
heterodimers
holo
maintains
modelling
ngfi
pocket
relieve
rxr
rxralpha
rxralphaf318a
shifting
thermodynamic
transcriptionally
van
waals
Tagcloud (Difference)
?
adopt
af
agonists
allowing
apo
bms614
competent
constitutive
corepressor
der
disabled
disrupts
h11
heterodimerization
heterodimers
holo
maintains
modelling
ngfi
pocket
relieve
rxr
rxralpha
rxralphaf318a
shifting
thermodynamic
transcriptionally
van
waals
Tagcloud (Intersection)
?