LBP and TRA2A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		LBP	TRA2A
Gene Name		lipopolysaccharide binding protein	transformer 2 alpha homolog (Drosophila)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Cell Surface Extracellular Vesicular Exosome	Nucleus Nucleolus Intracellular Membrane-bounded Organelle
	Molecular Function	Lipopolysaccharide Binding Receptor Binding Protein Binding Lipoteichoic Acid Binding	Nucleotide Binding Poly(A) RNA Binding
	Biological Process	Toll-like Receptor Signaling Pathway Leukocyte Chemotaxis Involved In Inflammatory Response Macrophage Activation Involved In Immune Response Acute-phase Response Cellular Defense Response Opsonization Lipopolysaccharide Transport Lipopolysaccharide-mediated Signaling Pathway Detection Of Molecule Of Bacterial Origin Response To Lipopolysaccharide Negative Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Positive Regulation Of Macrophage Activation Negative Regulation Of Growth Of Symbiont In Host Innate Immune Response Defense Response To Gram-negative Bacterium Defense Response To Gram-positive Bacterium Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Cellular Response To Lipopolysaccharide Cellular Response To Lipoteichoic Acid Positive Regulation Of Neutrophil Chemotaxis	MRNA Splicing, Via Spliceosome
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 4 (TLR4) Cascade Transfer of LPS from LBP carrier to CD14 Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		19 interactors: APOA1 BAG6 BST1 C4BPA CAMP CBFA2T2 CD14 CFHR1 FTH1 HSPB1 IRF6 PRDX4 PSMA3 PYCRL RPS21 SETD1A SMAD3 TRA2A TSC22D4	17 interactors: C11orf58 CDK2AP2 CDK6 CRABP1 DHX15 LBP NUDT21 NXF1 PPP1CC RNPS1 SELENBP1 SRPK2 SRSF10 TNNT1 U2SURP YTHDC1 YWHAG
Entrez ID		3929	29896
HPRD ID		07175	04096
Ensembl ID		ENSG00000129988	ENSG00000164548
Uniprot IDs		P18428 Q8TCF0	B4DUA9 Q13595 Q549U1
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune System Process Immune Response Regulation Of Interleukin-1 Beta Production Regulation Of Cell Proliferation Humoral Immune Response Protein Stabilization Response To Stress Regulation Of Protein Stability Positive Regulation Of Interleukin-1 Beta Production Regulation Of Protein Catabolic Process Positive Regulation Of Interleukin-1 Production Regulation Of Immune System Process Posttranscriptional Regulation Of Gene Expression Regulation Of Immune Response Positive Regulation Of Stress Fiber Assembly Response To Stimulus Negative Regulation Of Protein Metabolic Process Positive Regulation Of Actin Filament Bundle Assembly Gene Expression Regulation Of Cytokine Production Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Male Germ Cell Proliferation Negative Regulation Of Cell Adhesion Molecule Production Negative Regulation Of Growth Of Symbiont On Or Near Host Surface Regulation Of Protein Metabolic Process Positive Regulation Of Tumor Necrosis Factor Production I-kappaB Kinase/NF-kappaB Signaling Cell Cycle Process Regulation Of Stress Fiber Assembly Regulation Of Inflammatory Response Negative Regulation Of Cell Proliferation Regulation Of Opsonization Intracellular Sequestering Of Iron Ion Negative Regulation Of Interleukin-1 Beta Secretion Sister Chromatid Biorientation Response To Other Organism Positive Regulation Of Protein Metabolic Process Epithelial Cell Proliferation Intracellular Signal Transduction Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import Endonucleolytic Cleavage To Generate Mature 3'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Male Germ Cell Proliferation Evasion Or Tolerance Of Host Defenses By Virus Response To Biotic Stimulus Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cytokine Production Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Metabolic Process Negative Regulation Of Inflammatory Response	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process Spliceosomal Complex Assembly MRNA Export From Nucleus Regulation Of MRNA Splicing, Via Spliceosome RNA Export From Nucleus Regulation Of MRNA Processing Regulation Of RNA Splicing MRNA Transport Nuclear Export Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing RNA Transport RNA Localization Ribonucleoprotein Complex Assembly Termination Of RNA Polymerase II Transcription MRNA Splice Site Selection Nucleocytoplasmic Transport Nuclear Transport Cell Dedifferentiation Nuclear Speck Organization Gene Expression DNA-templated Transcription, Termination Ribonucleoprotein Complex Biogenesis MRNA 3'-end Processing Positive Regulation Of Respiratory Burst Involved In Inflammatory Response Leukocyte Chemotaxis Involved In Inflammatory Response Lipopolysaccharide Transport RNA 3'-end Processing RNA Metabolic Process Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Slow-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Respiratory Burst Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Cellular Senescence Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death
Tagcloud ?		adopt af agonists allowing apo bms614 competent constitutive corepressor der disabled disrupts h11 heterodimerization heterodimers holo maintains modelling ngfi pocket relieve rxr rxralpha rxralphaf318a shifting thermodynamic transcriptionally van waals
Tagcloud (Difference) ?		adopt af agonists allowing apo bms614 competent constitutive corepressor der disabled disrupts h11 heterodimerization heterodimers holo maintains modelling ngfi pocket relieve rxr rxralpha rxralphaf318a shifting thermodynamic transcriptionally van waals
Tagcloud (Intersection) ?