LDLRAD1 and MAL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		LDLRAD1	MAL
Description		low density lipoprotein receptor class A domain containing 1	mal, T cell differentiation protein (MAL blood group)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Endoplasmic Reticulum Plasma Membrane Membrane Apical Plasma Membrane Schmidt-Lanterman Incisure Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Vesicle-mediated Transport	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Central Nervous System Myelination Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)
Interacting Genes		34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1	81 interacting genes: AMHR2 AQP6 BCL2L13 BTN2A1 CALN1 CD300LG CD3G CD40 CD53 CD69 CLDN14 CLDN20 CLDN7 CLDN9 CLEC4C CLSTN3 CPLX4 CREB3L1 CXADR DAGLA EDA EMP1 EVI2A FAM209A FCRL2 FIBCD1 FNDC9 GJA8 GJB1 GPR152 GRAMD1A GSG1L HIBADH IL10RA IL20RB JAML KCNA1 KCNA10 KCNMB4 KLRC1 LDLRAD1 LMAN2L LMNA LRRC25 LRTM1 LSMEM1 MC4R MS4A4A MYD88 NCAPH2 NKAIN4 NPDC1 OPRM1 PERP PLA2G10 PRRT1 PTPRN RAMP1 SDC4 SGCB SHISA3 SHISA4 SLC10A1 SLC35H1 SMIM3 SPINT1 STX1A SYNDIG1 TEX29 TIGIT TM4SF18 TMEM106C TMEM174 TMEM207 TMEM213 TMEM248 TMEM30A TMEM52B TNFSF14 TSPO2 USP7
Entrez ID		388633	4118
HPRD ID		17372	01789
Ensembl ID		ENSG00000203985	ENSG00000172005
Uniprot IDs		Q5T700	P21145
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Presynaptic Endosome Membrane Cellular Response To Mercury Ion Positive Regulation Of Membrane Permeability Lysosome Nuclear Envelope Response To Mercury Ion Mitochondrial Protein Catabolic Process Endoplasmic Reticulum Membrane Mitochondrial Outer Membrane Permeabilization Structural Constituent Of Myelin Sheath Response To Oxygen-glucose Deprivation Neurotransmitter Receptor Transport To Plasma Membrane Defense Response To Virus Negative Regulation Of Mitochondrial Membrane Potential Protein Binding Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Regulation Of Membrane Permeability Neurotransmitter Receptor Transport Response To Oxygen Levels Endoplasmic Reticulum Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Establishment Of Protein Localization Golgi To Vacuole Transport Establishment Of Protein Localization To Membrane Lysosomal Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Defense Response Nitric Oxide Transmembrane Transporter Activity Negative Regulation Of Programmed Cell Death Metanephric Proximal Convoluted Tubule Segment 2 Development Nuclear Membrane Membrane Organization Response To Virus Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Mitochondrion Autophagosome Adaptor Activity Hair Follicle Morphogenesis Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Vesicle-mediated Transport D-aspartate Transmembrane Transporter Activity	Membrane Plasma Membrane Protein Binding Gamma-delta T Cell Activation Anchoring Junction Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Postsynaptic Density Membrane Cell-cell Junction Organization Bicellular Tight Junction Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell Junction Organization Bicellular Tight Junction Assembly Tight Junction Assembly Tight Junction Organization Structural Molecule Activity Cell-cell Junction Assembly Leukocyte Activation
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