LDLRAD1 and TMEM218

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		LDLRAD1	TMEM218
Description		low density lipoprotein receptor class A domain containing 1	transmembrane protein 218
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane	Cilium Membrane Cell Projection
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Parkinson disease and lewy body pathology ( 25663231)	Breast cancer (survival) ( 25890600) Familial lung adenocarcinoma ( 29924316)
Interacting Genes		34 interacting genes: ADGRG7 ANKRD46 AQP1 BNIP2 BNIP3 BNIP3L CMTM7 CTXN3 CXCL9 EBP EMP3 GIMAP5 GPR25 IGFBP5 LAPTM5 MAL MALL MARCHF2 NINJ2 OLFM4 PLN PLPP6 PTTG1IP SEC22A SLC1A1 SLC41A2 TMEM147 TMEM190 TMEM218 TMEM79 UNC93B1 VAMP4 VTI1B ZFPL1	75 interacting genes: APH1A AQP2 AQP6 ARL13B ASZ1 ATP6V0E1 BSCL2 CD300A CD53 CD79A CLDN2 CLEC10A CLEC17A CPLX4 CREB3L1 CTLA4 DAGLA EBP ELOVL2 ELOVL4 EMP1 ERGIC3 FAM209A FCER1G FFAR2 FRMD3 GDAP1 GJB1 GJB4 GJB6 GPR152 GPR61 GPX8 HSD17B13 IFNGR2 KCNJ6 KCNK5 KIR2DL3 LDLRAD1 LHFPL5 LMNA LSMEM2 MFF MS4A3 MTIF3 MUC1 NPFFR2 PCNA PDCD1LG2 PIK3IP1 PLEKHO1 PSCA RETREG3 SAR1A SDC3 SLC10A4 SLC10A6 SLC18A1 SMIM3 SSMEM1 TM4SF18 TMED8 TMEM106C TMEM182 TMEM207 TMEM234 TMEM31 TMEM45B TMEM52B TMEM88 TMPRSS2 TRHR TSPAN12 TSPAN18 VSIR
Entrez ID		388633	219854
HPRD ID		17372	19054
Ensembl ID		ENSG00000203985	ENSG00000150433
Uniprot IDs		Q5T700	A2RU14 E9PI23
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Presynaptic Endosome Membrane Cellular Response To Mercury Ion Positive Regulation Of Membrane Permeability Lysosome Nuclear Envelope Response To Mercury Ion Mitochondrial Protein Catabolic Process Endoplasmic Reticulum Membrane Mitochondrial Outer Membrane Permeabilization Structural Constituent Of Myelin Sheath Response To Oxygen-glucose Deprivation Neurotransmitter Receptor Transport To Plasma Membrane Defense Response To Virus Negative Regulation Of Mitochondrial Membrane Potential Protein Binding Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Regulation Of Membrane Permeability Neurotransmitter Receptor Transport Response To Oxygen Levels Endoplasmic Reticulum Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Establishment Of Protein Localization Golgi To Vacuole Transport Establishment Of Protein Localization To Membrane Lysosomal Membrane Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Defense Response Nitric Oxide Transmembrane Transporter Activity Negative Regulation Of Programmed Cell Death Metanephric Proximal Convoluted Tubule Segment 2 Development Nuclear Membrane Membrane Organization Response To Virus Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Mitochondrion Autophagosome Adaptor Activity Hair Follicle Morphogenesis Negative Regulation Of Skeletal Muscle Hypertrophy Protein Insertion Into Plasma Membrane Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Vesicle-mediated Transport D-aspartate Transmembrane Transporter Activity	Membrane Plasma Membrane Protein Binding Connexin Complex Regulation Of Myoblast Fusion Gap Junction Channel Activity Gap Junction Bile Acid:sodium Symporter Activity Fatty Acid Elongation, Monounsaturated Fatty Acid Fatty Acid Elongase Activity Fatty Acid Elongation, Polyunsaturated Fatty Acid Fucose Binding Gap Junction-mediated Intercellular Transport Renal Water Transport Gap Junction Assembly Fatty Acid Elongation, Saturated Fatty Acid
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