LDLRAD1 and VTI1B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LDLRAD1	VTI1B
Gene Name		low density lipoprotein receptor class A domain containing 1	vesicle transport through interaction with t-SNAREs 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Late Endosome Membrane Vesicle Neuronal Cell Body Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function		SNARE Binding SNAP Receptor Activity Chloride Channel Inhibitor Activity
	Biological Process		Autophagic Vacuole Fusion Protein Targeting To Vacuole ER To Golgi Vesicle-mediated Transport Intra-Golgi Vesicle-mediated Transport Golgi To Vacuole Transport Vesicle Docking Involved In Exocytosis Cell Proliferation Vesicle-mediated Transport Retrograde Transport, Endosome To Golgi Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: BNIP3 BNIP3L GIMAP5 GPR128 LAPTM5 MAL MALL MARCH2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B	10 interactors: GOLGB1 KRTAP10-7 LDLRAD1 PTPN5 STX4 STX7 STX8 SYNE4 TNK2 TRIM59
Entrez ID		388633	10490
HPRD ID		17372	04440
Ensembl ID			ENSG00000100568
Uniprot IDs		B7ZME3 Q5T700	Q9UEU0
PDB IDs			2V8S
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Defense Response To Virus Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Transport Protein Homooligomerization Response To Virus Mitochondrial Membrane Organization Cysteine Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Apoptotic Mitochondrial Changes Membrane Organization Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein Oligomerization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity D-aspartate Import Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Localization Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Mitochondrial Transport Negative Regulation Of Calcium Ion Import Autophagic Cell Death Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cellular Response To Cobalt Ion Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Cell Death Golgi To Vacuole Transport Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus	Vesicle Fusion Regulation Of Protein Localization To Plasma Membrane Organelle Fusion Membrane Fusion Vesicle Organization Vesicle Docking Positive Regulation Of Receptor Localization To Synapse Membrane Docking Positive Regulation Of Eosinophil Degranulation Vesicle-mediated Transport Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of Protein Localization Membrane Organization Regulation Of Cellular Component Organization Positive Regulation Of Protein Localization To Cell Surface Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Intracellular Protein Transport Positive Regulation Of Immunoglobulin Secretion SNARE Complex Assembly Establishment Of Monopolar Cell Polarity Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Cellular Localization Regulation Of Clathrin-mediated Endocytosis Regulation Of Immunoglobulin Secretion Establishment Of Epithelial Cell Polarity Regulation Of Vesicle-mediated Transport Regulation Of Protein Localization To Cell Surface Positive Regulation Of Regulated Secretory Pathway Early Endosome To Late Endosome Transport Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Response To Hydroperoxide Organelle Localization Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Morphogenesis Of A Polarized Epithelium Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cellular Protein Localization Positive Regulation Of Protein Localization To Plasma Membrane Protein Transport Establishment Or Maintenance Of Apical/basal Cell Polarity Endosome To Lysosome Transport Establishment Of Protein Localization Intracellular Transport Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Immunoglobulin Production Regulation Of Regulated Secretory Pathway Organelle Organization
Tagcloud ?			autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative snare snares vacuole vacuoles vamp3 vamp7 vamp8 vti1a
Tagcloud (Difference) ?			autophagic autophagolysosomal bacterium biogenesis burnetii chloramphenicol colocalization coxiella crv crvs endocytic endolysosomal facilitating favours heterotypic homotypic lysosomes nt phagolysosomal phagosomes replicative snare snares vacuole vacuoles vamp3 vamp7 vamp8 vti1a
Tagcloud (Intersection) ?