LDLRAD1 and MARCH2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		LDLRAD1	MARCH2
Gene Name		low density lipoprotein receptor class A domain containing 1	membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane	Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endosome Membrane Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function		Ubiquitin-protein Transferase Activity Zinc Ion Binding Ligase Activity
	Biological Process		Endocytosis Protein Ubiquitination
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: BNIP3 BNIP3L GIMAP5 GPR128 LAPTM5 MAL MALL MARCH2 OLFM4 PLN PTTG1IP SLC1A1 TMEM147 TMEM190 TMEM218 VTI1B	8 interactors: CCDC155 CDC34 FATE1 LDLRAD1 STX6 SYNE4 UBE2D1 UBE2H
Entrez ID		388633	51257
HPRD ID		17372	14361
Ensembl ID			ENSG00000099785
Uniprot IDs		B7ZME3 Q5T700	Q9P0N8
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Mitochondrial Outer Membrane Permeabilization Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Defense Response To Virus Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Transport Protein Homooligomerization Response To Virus Mitochondrial Membrane Organization Cysteine Transport Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Cytotoxic T Cell Differentiation Intrinsic Apoptotic Signaling Pathway In Response To Hypoxia Negative Regulation Of Calcium-transporting ATPase Activity TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Apoptotic Mitochondrial Changes Membrane Organization Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Negative Regulation Of Calcium Ion Binding Regulation Of The Force Of Heart Contraction By Cardiac Conduction Protein Oligomerization Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Membrane Raft Polarization Regulation Of Calcium-transporting ATPase Activity D-aspartate Import Adrenergic Receptor Signaling Pathway Involved In Heart Process Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Localization Negative Regulation Of Mitochondrial Fusion Granzyme-mediated Apoptotic Signaling Pathway Mitochondrial Transport Negative Regulation Of Calcium Ion Import Autophagic Cell Death Regulation Of Mitochondrial Fusion Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Cellular Response To Cobalt Ion Regulation Of Relaxation Of Cardiac Muscle Positive Regulation Of Cell Death Golgi To Vacuole Transport Negative Regulation Of ATPase Activity Regulation Of Relaxation Of Muscle Vesicle Fusion With Golgi Apparatus	Protein K48-linked Ubiquitination Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Chromosome Localization To Nuclear Envelope Involved In Synapsis Cellular Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Macromolecule Catabolic Process Establishment Of Epithelial Cell Apical/basal Polarity Cell Cycle Process Positive Regulation Of Inclusion Body Assembly Golgi Ribbon Formation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Negative Regulation Of CAMP-mediated Signaling Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Cell Cycle Establishment Of Epithelial Cell Polarity Proteolysis Regulation Of Inclusion Body Assembly Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Regulation Of CAMP-mediated Signaling Protein K11-linked Ubiquitination
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