POLR1C and CORO1B

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POLR1C	CORO1B
Gene Name		polymerase (RNA) I polypeptide C, 30kDa	coronin, actin binding protein, 1B
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA-directed RNA Polymerase III Complex DNA-directed RNA Polymerase I Complex Cytosol	Stress Fiber Cytoplasm Actin Filament Plasma Membrane Focal Adhesion Actin Cytoskeleton Lamellipodium Cell Leading Edge Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Dimerization Activity	Protein Binding Identical Protein Binding Actin Filament Binding Arp2/3 Complex Binding
	Biological Process	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Regulation Of Gene Expression, Epigenetic Innate Immune Response Negative Regulation Of Gene Expression, Epigenetic	Cell Migration Actin Cytoskeleton Organization Ruffle Organization Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endothelial Cell Chemotaxis Wound Healing Actin Filament Bundle Assembly Actin Filament Branching Protein Localization To Cell Leading Edge Positive Regulation Of Lamellipodium Morphogenesis
Pathways		RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Cytosolic sensors of pathogen-associated DNA Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Termination NoRC negatively regulates rRNA expression RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Chain Elongation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ATRIP BIRC7 CCDC33 CCDC36 CD3EAP CLU CORO1A CORO1B FAM154A FAM208B IKZF3 KCTD1 KRT19 LZTS2 MBIP MYD88 MYO5B NFKBIB NME1 POLR1D POLR1E POLR2J PPP2R3C RIMBP3 SMN2 TCF4 TNFAIP1 TRIM27 TRIOBP TSC22D4 VIM WRN	6 interactors: ARPC2 KPNA2 POLR1C PRKCA SSH1 TERF1
Entrez ID		9533	57175
HPRD ID		09661	16743
Ensembl ID		ENSG00000171453	ENSG00000172725
Uniprot IDs		O15160	Q9BR76
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production Cytoskeleton Organization DNA-templated Transcription, Elongation Cellular Component Assembly Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase I Promoter Response To Stress Actin Filament-based Process Transcription From RNA Polymerase I Promoter Regulation Of Type I Interferon Production Organelle Organization Innate Immune Response Regulation Of Cytokine Production Nucleobase-containing Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Actin Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cytokine Production Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune Response Immune System Process DNA-templated Transcription, Termination Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transcription, DNA-templated Negative Regulation Of Actin Nucleation Response To Stimulus Regulation Of Apoptotic Process RNA Biosynthetic Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Cell Death Glial Cell Development Biosynthetic Process Nitrogen Compound Metabolic Process RRNA Transcription Cellular Process Actin Filament Organization Regulation Of Actin Nucleation RNA Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Immune System Process	Regulation Of Lamellipodium Assembly Positive Regulation Of Cellular Component Biogenesis Regulation Of Cytoskeleton Organization Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Protein Polymerization Positive Regulation Of Mitotic Cell Cycle Regulation Of Cell Projection Assembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Histone H3-T6 Phosphorylation Innate Immune Response Telomeric Loop Formation Age-dependent Telomere Shortening Positive Regulation Of Protein Complex Assembly Telomere Maintenance Via Telomere Shortening Regulation Of Organelle Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Negative Regulation Of Telomere Maintenance Via Telomerase Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Response To Stimulus Positive Regulation Of Cell Cycle Desmosome Assembly Replicative Cell Aging Cellular Response To ATP Negative Regulation Of Glial Cell Apoptotic Process Negative Regulation Of Transferase Activity Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Cellular Component Size Negative Regulation Of Glucose Import Regulation Of Telomere Maintenance Via Telomerase Regulation Of Protein Complex Assembly Immune Response Positive Regulation Of Macrophage Differentiation Defense Response Desmosome Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cell Adhesion Organelle Organization Regulation Of Telomerase Activity Positive Regulation Of Lamellipodium Assembly Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process
Tagcloud ?		add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Difference) ?		add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing	abomasum actb b2m blat butterfat calculating cops7a cows dnajc19 eif3k emd gapdh genorm golga5 goodness gpr175 icg linoleic lipogenic marveld1 mine mrpl39 mtg1 normalization qpcr supplements unsupplemented uxt verification
Tagcloud (Intersection) ?