POLR1C and TRIOBP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		POLR1C	TRIOBP
Gene Name		polymerase (RNA) I polypeptide C, 30kDa	TRIO and F-actin binding protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA-directed RNA Polymerase III Complex DNA-directed RNA Polymerase I Complex Cytosol	Nucleus Cytoplasm Microtubule Organizing Center Focal Adhesion Actin Cytoskeleton Midbody
	Molecular Function	RNA Polymerase I Activity RNA Polymerase III Activity DNA Binding DNA-directed RNA Polymerase Activity Protein Dimerization Activity	GTP-Rho Binding Ubiquitin Protein Ligase Binding Myosin II Binding Actin Filament Binding
	Biological Process	Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase III Promoter Transcription Elongation From RNA Polymerase III Promoter Termination Of RNA Polymerase III Transcription Gene Expression Positive Regulation Of Type I Interferon Production Regulation Of Gene Expression, Epigenetic Innate Immune Response Negative Regulation Of Gene Expression, Epigenetic	Mitotic Nuclear Division Actin Modification Barbed-end Actin Filament Capping Cell Division Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Cytosolic sensors of pathogen-associated DNA Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Termination NoRC negatively regulates rRNA expression RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Chain Elongation Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ATRIP BIRC7 CCDC33 CCDC36 CD3EAP CLU CORO1A CORO1B FAM154A FAM208B IKZF3 KCTD1 KRT19 LZTS2 MBIP MYD88 MYO5B NFKBIB NME1 POLR1D POLR1E POLR2J PPP2R3C RIMBP3 SMN2 TCF4 TNFAIP1 TRIM27 TRIOBP TSC22D4 VIM WRN	6 interactors: GTF2H1 HECTD3 IKBKG PLK1 POLR1C VIM
Entrez ID		9533	11078
HPRD ID		09661	11028
Ensembl ID		ENSG00000171453	ENSG00000100106
Uniprot IDs		O15160	F8W6V6 Q9H2D6
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production Cytoskeleton Organization DNA-templated Transcription, Elongation Cellular Component Assembly Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter DNA-templated Transcription, Initiation Transcription Initiation From RNA Polymerase I Promoter Response To Stress Actin Filament-based Process Transcription From RNA Polymerase I Promoter Regulation Of Type I Interferon Production Organelle Organization Innate Immune Response Regulation Of Cytokine Production Nucleobase-containing Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Heterocycle Metabolic Process Actin Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cytokine Production Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Immune Response Immune System Process DNA-templated Transcription, Termination Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Transcription, DNA-templated Negative Regulation Of Actin Nucleation Response To Stimulus Regulation Of Apoptotic Process RNA Biosynthetic Process Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Regulation Of Metabolic Process Regulation Of Tumor Necrosis Factor Production Regulation Of Cell Death Glial Cell Development Biosynthetic Process Nitrogen Compound Metabolic Process RRNA Transcription Cellular Process Actin Filament Organization Regulation Of Actin Nucleation RNA Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Immune System Process	Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription From RNA Polymerase I Promoter DNA-templated Transcription, Termination Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production DNA-templated Transcription, Elongation Viral Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Type I Interferon Production Activation Of APC-Cdc20 Complex Activity Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Cellular Response To DNA Damage Stimulus Cellular Macromolecule Catabolic Process Polar Body Extrusion After Meiotic Divisions Regulation Of Gene Expression, Epigenetic DNA-templated Transcription, Initiation Regulation Of Protein Phosphorylation Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Bergmann Glial Cell Differentiation Positive Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Gene Expression Metaphase/anaphase Transition Of Mitotic Cell Cycle Regulation Of Phosphorylation Protein Localization To Chromatin Negative Regulation Of Gene Expression Positive Regulation Of Cytokine Production Positive Regulation Of Peptidyl-threonine Phosphorylation Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Chromosome Segregation Regulation Of Phosphorus Metabolic Process Cellular Response To Stress Positive Regulation Of Gene Expression Intermediate Filament Organization Nucleotide-excision Repair, DNA Damage Removal Lens Fiber Cell Development Positive Regulation Of Metabolic Process Response To Stress Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Astrocyte Development Ubiquitin-dependent Protein Catabolic Process Protein Destabilization Modification-dependent Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway
Tagcloud ?		add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing
Tagcloud (Difference) ?		add biosynthesis burgeoning codified codifies collins constituent crest disrupts elucidating genetics hemizygous heterozygosity illustrating implicates nascent neuroepithelium pathophysiology planning playing researchers ribosome tcof1 tcs treacher treacle underpinnings utilizing
Tagcloud (Intersection) ?