HSPA1B and DNMBP

Number of citations of the paper that reports this interaction (PMID 14506234)
39

Data Source:
HPRD (in vitro)

		HSPA1B	DNMBP
Gene Name		heat shock 70kDa protein 1B	dynamin binding protein
Image
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Centriole Cytosol Focal Adhesion COP9 Signalosome Inclusion Body Aggresome Nuclear Speck Ribonucleoprotein Complex Vesicle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Blood Microparticle	Golgi Stack Cytoskeleton Cell Junction Synapse
	Molecular Function	Virus Receptor Activity G-protein Coupled Receptor Binding Double-stranded RNA Binding Protein Binding ATP Binding ATPase Activity Enzyme Binding Heat Shock Protein Binding Ubiquitin Protein Ligase Binding ATPase Activity, Coupled Protein Binding Involved In Protein Folding Poly(A) RNA Binding Protein N-terminus Binding Unfolded Protein Binding	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	MRNA Catabolic Process Response To Unfolded Protein Negative Regulation Of Cell Proliferation Response To Virus Gene Expression Regulation Of Cell Death Negative Regulation Of Cell Growth Negative Regulation Of Protein Ubiquitination Cellular Response To Oxidative Stress Cellular Response To Heat Protein Refolding Negative Regulation Of Apoptotic Process Positive Regulation Of Erythrocyte Differentiation Protein Stabilization Negative Regulation Of Cell Death Cellular Heat Acclimation Negative Regulation Of Inclusion Body Assembly Regulation Of Cellular Response To Heat Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Viral RNP Complexes in the Host Cell Nucleus Attenuation phase Regulation of HSF1-mediated heat shock response Cellular response to heat stress AUF1 (hnRNP D0) destabilizes mRNA Influenza Infection Influenza Life Cycle HSF1-dependent transactivation Export of Viral Ribonucleoproteins from Nucleus
Drugs		Adenosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		10 interactors: AIFM1 BAG1 DNMBP HSPBP1 PGAM5 STUB1 SUMO4 TGM2 YWHAB YWHAZ	19 interactors: ACTA1 ARHGAP17 BIN3 BUB1B CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAPH1 VASP WASF1 WASL WIPF2
Entrez ID		3304	23268
HPRD ID		06784	10918
Ensembl ID		ENSG00000204388	ENSG00000107554
Uniprot IDs		A8K5I0 P08107	Q6XZF7
PDB IDs		1HJO 1S3X 1XQS 2E88 2E8A 2LMG 3A8Y 3ATU 3ATV 3AY9 3D2E 3D2F 3JXU 3LOF 4J8F	1UG1 1UHC 4GLM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Programmed Cell Death Cell Death Death Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Apoptotic Process Positive Regulation Of Catalytic Activity Regulation Of Cell Death Positive Regulation Of Proteolysis Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Mitochondrion Positive Regulation Of Proteasomal Protein Catabolic Process Apoptotic Process Intracellular Signal Transduction Regulation Of Cellular Protein Metabolic Process Regulation Of Mitochondrion Organization Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Chaperone-mediated Protein Complex Assembly Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Negative Regulation Of Motor Neuron Apoptotic Process Positive Regulation Of Protein Ubiquitination Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Signal Transduction Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Golgi Reassembly Positive Regulation Of Cellular Protein Catabolic Process Response To Endoplasmic Reticulum Stress Regulation Of Proteolysis Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Dephosphorylation Histamine Secretion By Mast Cell Chaperone Cofactor-dependent Protein Refolding Salivary Gland Cavitation Signaling Cell Communication Establishment Of Golgi Localization Ubiquitin-dependent SMAD Protein Catabolic Process Cellular Metabolic Process Regulation Of Proteasomal Protein Catabolic Process	Actin Cytoskeleton Organization Actin Filament-based Process Actin Filament Organization Cytoskeleton Organization Actin Polymerization Or Depolymerization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Organelle Organization Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytoskeleton Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Movement Of Cell Or Subcellular Component Regulation Of Actin Nucleation Immune Response-regulating Signaling Pathway Regulation Of Cell Projection Assembly Axonogenesis Locomotion Positive Regulation Of Immune System Process Axon Development Cell Development Cell Morphogenesis Involved In Neuron Differentiation Anatomical Structure Morphogenesis Cellular Response To Stimulus Regulation Of Cellular Component Organization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Communication Positive Regulation Of Immune Response Neuron Projection Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Morphogenesis Axon Guidance Response To Stimulus Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Cell Morphogenesis Involved In Differentiation Cell Projection Organization Signal Transduction Neuron Projection Development Regulation Of Cell Projection Organization Cell Projection Morphogenesis Regulation Of Cytoskeleton Organization Regulation Of Immune System Process Response To External Stimulus Cell Part Morphogenesis Regulation Of Immune Response Signaling Cell Surface Receptor Signaling Pathway
Tagcloud ?		alphascreen ammp calnexin cndp2 combines hsp90b1 hspa5 hspa9 identifier imbalance itraq nfhcc nonfibrotic nontumor p4hb pdia6 phosphoproteomics pointed proteomexchange proteomics proteostasis pxd001253 resident ser583 txn ubc unraveling vcp
Tagcloud (Difference) ?		alphascreen ammp calnexin cndp2 combines hsp90b1 hspa5 hspa9 identifier imbalance itraq nfhcc nonfibrotic nontumor p4hb pdia6 phosphoproteomics pointed proteomexchange proteomics proteostasis pxd001253 resident ser583 txn ubc unraveling vcp
Tagcloud (Intersection) ?