STRAP and C6orf203

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		STRAP	C6orf203
Gene Name		serine/threonine kinase receptor associated protein	chromosome 6 open reading frame 203
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane SMN Complex SMN-Sm Protein Complex	Mitochondrion
	Molecular Function	Receptor Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Spliceosomal SnRNP Assembly Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Migration Negative Regulation Of Epithelial To Mesenchymal Transition Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Epithelial Cell Proliferation Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathways		Loss of Function of TGFBR2 in Cancer TGFBR2 MSI Frameshift Mutants in Cancer SMAD2/3 Phosphorylation Motif Mutants in Cancer Loss of Function of SMAD2/3 in Cancer TGFBR2 Kinase Domain Mutants in Cancer Loss of Function of SMAD4 in Cancer Downregulation of TGF-beta receptor signaling SMAD2/3 MH2 Domain Mutants in Cancer TGFBR1 KD Mutants in Cancer TGF-beta receptor signaling activates SMADs TGFBR1 LBD Mutants in Cancer Loss of Function of TGFBR1 in Cancer Signaling by TGF-beta Receptor Complex Signaling by TGF-beta Receptor Complex in Cancer SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: C6orf203 CHEK2 GEMIN6 GEMIN7 MAP1B NXF1 PBLD PDPK1 RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO4 TGFBR1 TGFBR2	3 interactors: APP COPS5 STRAP
Entrez ID		11171	51250
HPRD ID		05816	12873
Ensembl ID		ENSG00000023734	ENSG00000130349
Uniprot IDs		B0AZV0 B4DNJ6 Q9Y3F4	J3KQ88 Q9P0P8
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Spliceosomal SnRNP Assembly Regulation Of Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Signaling Pathway NcRNA Metabolic Process Ribonucleoprotein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta RNA Processing MRNA Splicing, Via Spliceosome Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway RNA Splicing, Via Transesterification Reactions Regulation Of Epithelial To Mesenchymal Transition Cellular Macromolecular Complex Assembly Cellular Component Assembly Ribonucleoprotein Complex Biogenesis RNA Splicing Cellular Response To Growth Factor Stimulus Response To Growth Factor Gene Expression MRNA Processing Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Signal Transduction Regulation Of Pathway-restricted SMAD Protein Phosphorylation Pathway-restricted SMAD Protein Phosphorylation RNA Metabolic Process Embryonic Cranial Skeleton Morphogenesis MRNA Metabolic Process Negative Regulation Of Signaling Spliceosomal Complex Assembly Enzyme Linked Receptor Protein Signaling Pathway Regulation Of BMP Signaling Pathway Histone MRNA Metabolic Process Response To Cholesterol Regulation Of Cell Morphogenesis Zygotic Specification Of Dorsal/ventral Axis Activin Receptor Signaling Pathway Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Embryonic Skeletal System Morphogenesis Mesonephros Development Kidney Development Termination Of RNA Polymerase II Transcription Negative Regulation Of Protein Phosphorylation Renal System Development Negative Regulation Of BMP Signaling Pathway	Regulation Of Phosphorylation Synaptic Growth At Neuromuscular Junction Regulation Of Phosphorus Metabolic Process Collateral Sprouting In Absence Of Injury Exosomal Secretion Regulation Of Transcription From RNA Polymerase II Promoter Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of Cell Development Exocytosis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition MRNA Processing Cullin Deneddylation Neuron Remodeling Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation Protein Deneddylation Secretion By Cell MRNA Metabolic Process Regulation Of Signal Transduction RNA Processing Maintenance Of Gastrointestinal Epithelium Secretion Cellular Copper Ion Homeostasis Regulation Of Signaling Negative Regulation Of Epithelial To Mesenchymal Transition Epithelial Structure Maintenance RNA Metabolic Process Copper Ion Homeostasis Suckling Behavior Negative Regulation Of Cell Differentiation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Gene Expression Negative Regulation Of Cellular Protein Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Cell Development Negative Regulation Of Protein Metabolic Process Mating Behavior Negative Regulation Of Stem Cell Differentiation Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Cycle RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Spliceosomal SnRNP Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle
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Tagcloud (Difference) ?		behind board compression compressive conservative consider fundamental hyperflexed knee knees manufacturers nerve neuropathy nylon outrigger padding palsy participation peroneal predisposition recreational rider secured ski sport thighs tibia wish
Tagcloud (Intersection) ?