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STRAP and SNRPD2
Number of citations of the paper that reports this interaction (PMID
15848170
)
21
Data Source:
HPRD
(in vitro)
STRAP
SNRPD2
Gene Name
serine/threonine kinase receptor associated protein
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
SMN Complex
SMN-Sm Protein Complex
Nucleoplasm
Spliceosomal Complex
U1 SnRNP
U4 SnRNP
U12-type Spliceosomal Complex
Cytosol
Small Nuclear Ribonucleoprotein Complex
Methylosome
PICln-Sm Protein Complex
SMN-Sm Protein Complex
Extracellular Vesicular Exosome
Catalytic Step 2 Spliceosome
Molecular Function
Receptor Binding
Protein Binding
Poly(A) RNA Binding
Protein Binding
Poly(A) RNA Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Spliceosomal SnRNP Assembly
Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Epithelial Cell Migration
Negative Regulation Of Epithelial To Mesenchymal Transition
Maintenance Of Gastrointestinal Epithelium
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Spliceosomal Complex Assembly
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
RNA Splicing
Gene Expression
NcRNA Metabolic Process
Pathways
Loss of Function of TGFBR2 in Cancer
TGFBR2 MSI Frameshift Mutants in Cancer
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
TGFBR2 Kinase Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
Downregulation of TGF-beta receptor signaling
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 KD Mutants in Cancer
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
SMAD4 MH2 Domain Mutants in Cancer
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
snRNP Assembly
mRNA Splicing - Minor Pathway
Metabolism of non-coding RNA
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Subcutaneous adipose tissue (
22589738
)
Protein-Protein Interactions
24 interactors:
C6orf203
CHEK2
GEMIN6
GEMIN7
MAP1B
NXF1
PBLD
PDPK1
RN7SL1
RNU1-1
RNU2-1
SMAD2
SMAD3
SMAD6
SMAD7
SMN1
SMURF1
SNRPB
SNRPD2
SNRPD3
SNRPE
SUMO4
TGFBR1
TGFBR2
25 interactors:
CEP70
CLNS1A
DDX20
DMTN
EEF1G
EGFR
GEMIN2
GEMIN4
GEMIN5
GEMIN6
GEMIN7
IL7R
KAT5
LSM2
LSM6
OS9
SMN1
SMN2
SNRPD1
SNRPF
STRAP
STXBP2
STXBP3
WDR77
ZCCHC10
Entrez ID
11171
6633
HPRD ID
05816
03038
Ensembl ID
ENSG00000023734
ENSG00000125743
Uniprot IDs
B0AZV0
B4DNJ6
Q9Y3F4
P62316
PDB IDs
1B34
1VU2
1VU3
2Y9A
2Y9B
2Y9C
2Y9D
3CW1
3PGW
3S6N
4F77
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Spliceosomal SnRNP Assembly
Regulation Of Cellular Response To Growth Factor Stimulus
Transforming Growth Factor Beta Receptor Signaling Pathway
NcRNA Metabolic Process
Ribonucleoprotein Complex Assembly
Cellular Response To Transforming Growth Factor Beta Stimulus
Response To Transforming Growth Factor Beta
RNA Processing
MRNA Splicing, Via Spliceosome
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
RNA Splicing, Via Transesterification Reactions
Regulation Of Epithelial To Mesenchymal Transition
Cellular Macromolecular Complex Assembly
Cellular Component Assembly
Ribonucleoprotein Complex Biogenesis
RNA Splicing
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Gene Expression
MRNA Processing
Negative Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Negative Regulation Of Signal Transduction
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Pathway-restricted SMAD Protein Phosphorylation
RNA Metabolic Process
Embryonic Cranial Skeleton Morphogenesis
MRNA Metabolic Process
Negative Regulation Of Signaling
Spliceosomal Complex Assembly
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of BMP Signaling Pathway
Histone MRNA Metabolic Process
Response To Cholesterol
Regulation Of Cell Morphogenesis
Zygotic Specification Of Dorsal/ventral Axis
Activin Receptor Signaling Pathway
Ureteric Bud Development
Mesonephric Tubule Development
Mesonephric Epithelium Development
Embryonic Skeletal System Morphogenesis
Mesonephros Development
Kidney Development
Termination Of RNA Polymerase II Transcription
Negative Regulation Of Protein Phosphorylation
Renal System Development
Negative Regulation Of BMP Signaling Pathway
Spliceosomal SnRNP Assembly
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Ribonucleoprotein Complex Assembly
RNA Splicing
MRNA Processing
Ribonucleoprotein Complex Biogenesis
MRNA Metabolic Process
RNA Processing
NcRNA Metabolic Process
Cellular Macromolecular Complex Assembly
Cellular Component Assembly
Gene Expression
RNA Metabolic Process
Spliceosomal Complex Assembly
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Neutrophil Degranulation
Neutrophil Activation Involved In Immune Response
Cellular Response To Estradiol Stimulus
Neutrophil Mediated Immunity
Neutrophil Activation
Cellular Metabolic Process
Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic
Cellular Response To Estrogen Stimulus
Cellular Process
Leukocyte Degranulation
Alkanesulfonate Metabolic Process
Positive Regulation Of Platelet Aggregation
Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay
Regulated Secretory Pathway
Vesicle Docking Involved In Exocytosis
Protein Secretion By Platelet
Calcium-mediated Signaling Using Extracellular Calcium Source
Interleukin-7-mediated Signaling Pathway
Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling
Astrocyte Activation
Vesicle Docking
Regulation Of Epithelial Cell Proliferation
Actin Filament Reorganization
Membrane Docking
Activation Of Phospholipase A2 Activity
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Calcium-mediated Signaling
Cell Activation
Exocytosis
Tagcloud
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behind
board
compression
compressive
conservative
consider
fundamental
hyperflexed
knee
knees
manufacturers
nerve
neuropathy
nylon
outrigger
padding
palsy
participation
peroneal
predisposition
recreational
rider
secured
ski
sport
thighs
tibia
wish
Tagcloud (Difference)
?
behind
board
compression
compressive
conservative
consider
fundamental
hyperflexed
knee
knees
manufacturers
nerve
neuropathy
nylon
outrigger
padding
palsy
participation
peroneal
predisposition
recreational
rider
secured
ski
sport
thighs
tibia
wish
Tagcloud (Intersection)
?