KPNA1 and NUP54

Number of citations of the paper that reports this interaction (PMID 8707840)
58

Data Source:
BioGRID (pull down)

		KPNA1	NUP54
Gene Name		karyopherin alpha 1 (importin alpha 5)	nucleoporin 54kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Dendrite	Nuclear Envelope Nuclear Pore Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity	Nucleocytoplasmic Transporter Activity
	Biological Process	Regulation Of DNA Recombination Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Viral Process Viral Life Cycle Cytokine-mediated Signaling Pathway Positive Regulation Of Protein Import Into Nucleus Intracellular Transport Of Virus	Mitotic Cell Cycle Carbohydrate Metabolic Process Protein Targeting Nucleocytoplasmic Transport Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process MRNA Transport Transmembrane Transport
Pathways		Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism HIV Infection Host Interactions of HIV factors Interferon Signaling Apoptotic execution phase Integration of provirus Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Influenza Infection Antiviral mechanism by IFN-stimulated genes Early Phase of HIV Life Cycle Influenza Life Cycle HIV Life Cycle Activation of DNA fragmentation factor Transport of Ribonucleoproteins into the Host Nucleus Apoptosis induced DNA fragmentation Programmed Cell Death	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-Protein Interactions		32 interactors: ANP32A ANP32B BCAR3 CDKN1B CLK4 CRADD CSE1L ELAVL1 FOSL1 GOPC HDAC6 HIST2H2BE HIST3H3 IL1RAP KPNB1 LEF1 LMO4 NOSIP NUP50 NUP54 NUP62 ORC4 PAX5 RAG1 RANBP2 RUNX1T1 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5	14 interactors: AP2B1 APC CCDC85B DGCR6 HAUS1 HGS IFT20 KPNA1 KPNB1 KRT15 NUP62 NUPL1 NUTF2 SSR1
Entrez ID		3836	53371
HPRD ID		02819	06352
Ensembl ID		ENSG00000114030	ENSG00000138750
Uniprot IDs		B3KXZ2 P52294	B4DT35 Q7Z3B4
PDB IDs		2JDQ 3TJ3 4B18
Enriched GO Terms of Interacting Partners?		Response To Cytokine Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Cytokine-mediated Signaling Pathway Mitotic Nuclear Envelope Disassembly Cytoplasmic Transport Nuclear Envelope Disassembly Viral Process Nucleobase-containing Compound Metabolic Process Nucleus Organization RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Nuclear Envelope Organization Mitotic Cell Cycle Process Intracellular Transport Cellular Nitrogen Compound Metabolic Process Glucose Transport Regulation Of Cell Death Hexose Transport Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Viral Life Cycle Viral Transcription Cell Death Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Transport Response To Organic Substance Regulation Of Glucose Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Metabolic Process Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance MRNA Transport Regulation Of Proteolysis Carbohydrate Transport RNA Metabolic Process Apoptotic Process Establishment Of Localization In Cell RNA Transport	Protein Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Protein Localization Nucleocytoplasmic Transport Nuclear Transport Establishment Of Localization In Cell Cellular Localization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Viral Life Cycle Cellular Protein Localization Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Intracellular Protein Transport Protein Localization To Organelle Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Viral Process Execution Phase Of Apoptosis Regulation Of ERBB Signaling Pathway Establishment Of Protein Localization To Organelle Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Protein Targeting Cytokine-mediated Signaling Pathway Intracellular Transport Of Virus Cell Surface Receptor Signaling Pathway Apoptotic Nuclear Changes Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Cellular Response To Cytokine Stimulus Cellular Response To Organic Substance Mitotic Cell Cycle Process Transport Response To Cytokine Opsin Transport Nuclear Envelope Organization Mitotic Cell Cycle Signal Transduction Glucose Transport Hexose Transport Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process Membrane Organization Viral Transcription DNA Catabolic Process, Endonucleolytic Signaling Regulation Of Glucose Transport Negative Regulation Of Intracellular Signal Transduction Cell Communication Response To Organic Substance
Tagcloud ?		acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Difference) ?		acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Intersection) ?