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NUP54
Description
nucleoporin 54
Image
GO Annotations
Cellular Component
Nucleus
Nuclear Envelope
Nuclear Pore
Membrane
Nuclear Membrane
Nuclear Pore Central Transport Channel
Molecular Function
Protein Binding
Structural Constituent Of Nuclear Pore
Biological Process
NLS-bearing Protein Import Into Nucleus
Nucleocytoplasmic Transport
Nuclear Pore Organization
Protein Transport
Protein Localization To Nuclear Inner Membrane
MRNA Transport
Pathways
ISG15 antiviral mechanism
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript
Rev-mediated nuclear export of HIV RNA
Transport of Ribonucleoproteins into the Host Nucleus
NS1 Mediated Effects on Host Pathways
Viral Messenger RNA Synthesis
NEP/NS2 Interacts with the Cellular Export Machinery
Regulation of Glucokinase by Glucokinase Regulatory Protein
Nuclear import of Rev protein
Vpr-mediated nuclear import of PICs
IPs transport between nucleus and cytosol
IP3 and IP4 transport between cytosol and nucleus
IP6 and IP7 transport between cytosol and nucleus
snRNP Assembly
SUMOylation of DNA damage response and repair proteins
SUMOylation of ubiquitinylation proteins
Nuclear Pore Complex (NPC) Disassembly
Regulation of HSF1-mediated heat shock response
SUMOylation of SUMOylation proteins
SUMOylation of chromatin organization proteins
SUMOylation of RNA binding proteins
SUMOylation of DNA replication proteins
SUMOylation of DNA replication proteins
Transcriptional regulation by small RNAs
Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)
tRNA processing in the nucleus
HCMV Early Events
HCMV Late Events
Postmitotic nuclear pore complex (NPC) reformation
SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS
Age at first birth (
34211149
)
Hippocampal volume (
29274321
)
Novel Interacting Genes
3 novel interacting genes:
GOLIM4
SEPTIN11
THAP6
Interacting Genes
46 interacting genes:
AGR2
AIRIM
AP1B1
AP2B1
APC
BPIFA1
C14orf119
C21orf91
CCDC85B
CCHCR1
CDC23
CENPH
DCTN3
DGCR6
EFHC1
EIF3F
EXOC1
EXOC8
HAUS1
HAUS8
HGS
IFT20
KPNA1
KPNB1
KRT15
KRT27
KRT33B
NFKBID
NR3C1
NUP62
NUTF2
OGT
OIP5
PKNOX2
SMYD3
SOHLH1
SPG21
SSR1
TACC3
TCHP
TEKT1
TEX12
TPM3
TRIM54
VPS37C
ZWINT
Entrez ID
53371
HPRD ID
06352
Ensembl ID
ENSG00000138750
Uniprot IDs
A0A8Q3SHX2
A0A8Q3WLP2
Q7Z3B4
PDB IDs
4JNU
4JNV
4JO7
4JO9
5IJN
5IJO
7N8R
7PER
7R5J
7R5K
Enriched GO Terms of Interacting Partners
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Cytoskeleton
Cytoskeleton-dependent Cytokinesis
Centrosome
Organelle Assembly
Cell Division
Regulation Of Microtubule Cytoskeleton Organization
Spindle Organization
Establishment Of Protein Localization
Membrane Fission
Microtubule-based Process
Intracellular Protein Transport
Nuclear Import Signal Receptor Activity
Organelle Organization
Protein Transport
Mitotic Cytokinesis
Cytosol
Spindle
Cellular Localization
Chromosome Localization
Spindle Pole
Regulation Of Microtubule-based Process
Nuclear Pore
Protein Binding
Nuclear Pore Central Transport Channel
Membraneless Organelle Assembly
Keratin Filament
Mitotic Spindle Organization
Positive Regulation Of Protein Localization To Centrosome
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Regulation Of Microtubule Polymerization Or Depolymerization
Hsp90 Protein Binding
Metaphase/anaphase Transition Of Cell Cycle
HAUS Complex
Regulation Of Sister Chromatid Segregation
Vesicle Tethering Involved In Exocytosis
Intracellular Protein Localization
Mitotic Metaphase Chromosome Alignment
Organelle Localization
NLS-dependent Protein Nuclear Import Complex
Centrosome Cycle
Regulation Of Mitotic Nuclear Division
Protein Import Into Nucleus
Establishment Of Protein Localization To Organelle
Intracellular Transport
Protein Localization To Organelle
Import Into Nucleus
Clathrin Adaptor Complex
Regulation Of Protein Localization To Centrosome
Microtubule Cytoskeleton Organization Involved In Mitosis
Regulation Of Chromosome Segregation
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