KPNA1 and NOSIP

Number of citations of the paper that reports this interaction (PMID 16135813)
9

Data Source:
BioGRID (pull down)

		KPNA1	NOSIP
Gene Name		karyopherin alpha 1 (importin alpha 5)	nitric oxide synthase interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Dendrite	Golgi Membrane Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity	Protein Binding Poly(A) RNA Binding
	Biological Process	Regulation Of DNA Recombination Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Viral Process Viral Life Cycle Cytokine-mediated Signaling Pathway Positive Regulation Of Protein Import Into Nucleus Intracellular Transport Of Virus	Negative Regulation Of Catalytic Activity Small Molecule Metabolic Process Nitric Oxide Metabolic Process Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Nitric-oxide Synthase Activity
Pathways		Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism HIV Infection Host Interactions of HIV factors Interferon Signaling Apoptotic execution phase Integration of provirus Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Influenza Infection Antiviral mechanism by IFN-stimulated genes Early Phase of HIV Life Cycle Influenza Life Cycle HIV Life Cycle Activation of DNA fragmentation factor Transport of Ribonucleoproteins into the Host Nucleus Apoptosis induced DNA fragmentation Programmed Cell Death	Metabolism of nitric oxide NOSIP mediated eNOS trafficking eNOS activation and regulation
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-Protein Interactions		32 interactors: ANP32A ANP32B BCAR3 CDKN1B CLK4 CRADD CSE1L ELAVL1 FOSL1 GOPC HDAC6 HIST2H2BE HIST3H3 IL1RAP KPNB1 LEF1 LMO4 NOSIP NUP50 NUP54 NUP62 ORC4 PAX5 RAG1 RANBP2 RUNX1T1 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5	3 interactors: KPNA1 NOS1 NOS3
Entrez ID		3836	51070
HPRD ID		02819	17642
Ensembl ID		ENSG00000114030	ENSG00000142546
Uniprot IDs		B3KXZ2 P52294	Q9Y314
PDB IDs		2JDQ 3TJ3 4B18
Enriched GO Terms of Interacting Partners?		Response To Cytokine Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Cytokine-mediated Signaling Pathway Mitotic Nuclear Envelope Disassembly Cytoplasmic Transport Nuclear Envelope Disassembly Viral Process Nucleobase-containing Compound Metabolic Process Nucleus Organization RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Nuclear Envelope Organization Mitotic Cell Cycle Process Intracellular Transport Cellular Nitrogen Compound Metabolic Process Glucose Transport Regulation Of Cell Death Hexose Transport Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Viral Life Cycle Viral Transcription Cell Death Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Transport Response To Organic Substance Regulation Of Glucose Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Metabolic Process Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance MRNA Transport Regulation Of Proteolysis Carbohydrate Transport RNA Metabolic Process Apoptotic Process Establishment Of Localization In Cell RNA Transport	Arginine Catabolic Process Positive Regulation Of Guanylate Cyclase Activity Nitric Oxide Biosynthetic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nitric Oxide Mediated Signal Transduction Positive Regulation Of CGMP Biosynthetic Process Positive Regulation Of CGMP Metabolic Process Arginine Metabolic Process Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Potassium Ion Transport Regulation Of CGMP Biosynthetic Process Nitric Oxide Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of The Force Of Heart Contraction Regulation Of CGMP Metabolic Process Positive Regulation Of Vasodilation Negative Regulation Of Calcium Ion Transport Phagosome Maturation Regulation Of Vasodilation Positive Regulation Of Lyase Activity Negative Regulation Of Blood Pressure Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Regulation Of Cyclase Activity Positive Regulation Of Cyclic Nucleotide Metabolic Process Negative Regulation Of Translation Negative Regulation Of Ion Transport Epithelial Cell Migration Epithelium Migration Interaction With Host Reactive Oxygen Species Metabolic Process Response To Heat Cellular Amino Acid Catabolic Process Second-messenger-mediated Signaling Positive Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Regulation Of Heart Contraction Regulation Of Blood Pressure Ameboidal-type Cell Migration Response To Temperature Stimulus Regulation Of Calcium Ion Transport Carboxylic Acid Catabolic Process Negative Regulation Of Adrenergic Receptor Signaling Pathway Involved In Heart Process Smooth Muscle Hyperplasia Negative Regulation Of Serotonin Uptake Positive Regulation Of Adrenergic Receptor Signaling Pathway Negative Regulation Of Adrenergic Receptor Signaling Pathway Muscle System Process Regulation Of Translation Alpha-amino Acid Metabolic Process Catabolic Process
Tagcloud ?		acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Difference) ?		acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Intersection) ?