KLRC1 and MAL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLRC1	MAL
Gene Name		killer cell lectin-like receptor subfamily C, member 1	mal, T-cell differentiation protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Endosome Endoplasmic Reticulum Integral Component Of Plasma Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Membrane Raft
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Protein Antigen Binding	Protein Binding Lipid Binding Channel Activity Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of Immune Response	Membrane Raft Polarization Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Transmembrane Transport Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: HLA-E KLRD1 MAL PMP22 PTPN11 PTPN6	9 interactors: EDA FIBCD1 KLRC1 LDLRAD1 LSMEM1 MYD88 PTPRN SMIM3 USP7
Entrez ID		3821	4118
HPRD ID		01192	01789
Ensembl ID		ENSG00000134545	ENSG00000172005
Uniprot IDs		F5GYZ0 P26715	P21145
PDB IDs		2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle Regulation Of Innate Immune Response Innate Immune Response Regulation Of Immune Response Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Interferon-gamma-mediated Signaling Pathway Immune Response Regulation Of Immune System Process Defense Response Cellular Response To Interferon-gamma Megakaryocyte Development Response To Interferon-gamma Regulation Of ERK1 And ERK2 Cascade Platelet Formation Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Megakaryocyte Differentiation Regulation Of Response To Interferon-gamma Natural Killer Cell Mediated Immunity Myeloid Cell Differentiation Leukocyte Mediated Immunity Positive Regulation Of Immune System Process Immune System Process Positive Regulation Of Cell Activation Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Lymphocyte Activation Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Cell Activation T Cell Costimulation Signaling Cell Communication Cell Surface Receptor Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Cellular Response To Cytokine Stimulus Regulation Of MAPK Cascade Hemopoiesis Response To Stress Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade	Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Dense Core Granule Maturation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Response To Molecule Of Fungal Origin Trachea Gland Development Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Interleukin-23 Production Establishment Of Endothelial Intestinal Barrier Salivary Gland Cavitation Maintenance Of DNA Methylation Cellular Response To Stimulus Positive Regulation Of Interleukin-17 Production 3'-UTR-mediated MRNA Stabilization Type I Interferon Biosynthetic Process Positive Regulation Of Chemokine Biosynthetic Process Response To Peptidoglycan Toll Signaling Pathway Type I Interferon Production Cytokine-mediated Signaling Pathway Hair Follicle Placode Formation Histone Deubiquitination Positive Regulation Of NF-kappaB Import Into Nucleus Response To Stimulus Cytokine Biosynthetic Process Ectoderm Development MRNA Stabilization Negative Regulation Of Growth Of Symbiont In Host Cellular Response To Cytokine Stimulus Establishment Of Endothelial Barrier
Tagcloud ?			100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Difference) ?			100ng calyculin collagen formation forming gels genestien guinea ibmx il1 il3 il6 incorporation jak1 map megakaryocyte megakaryocytes okadaic phosphatase pig proplatelet proplatelets stat stimulate thymidine tpo transduction tyk unaffected
Tagcloud (Intersection) ?