KLRC1 and PMP22

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLRC1	PMP22
Gene Name		killer cell lectin-like receptor subfamily C, member 1	peripheral myelin protein 22
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Tight Junction Integral Component Of Membrane Compact Myelin
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding MHC Class I Protein Complex Binding Carbohydrate Binding Protein Antigen Binding	Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Regulation Of Immune Response	Synaptic Transmission Peripheral Nervous System Development Cell Death Negative Regulation Of Cell Proliferation Negative Regulation Of Neuron Projection Development Bleb Assembly Myelin Assembly
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Corneal structure ( 23291589)
Protein-Protein Interactions		6 interactors: HLA-E KLRD1 MAL PMP22 PTPN11 PTPN6	6 interactors: CANX DDX52 KLRC1 MPZ PEX19 SMIM3
Entrez ID		3821	5376
HPRD ID		01192	03059
Ensembl ID		ENSG00000134545	ENSG00000109099
Uniprot IDs		F5GYZ0 P26715	Q01453 Q6FH25
PDB IDs		2RMX 2YU7 3BDW 3CDG 3CII
Enriched GO Terms of Interacting Partners?		Abortive Mitotic Cell Cycle Regulation Of Innate Immune Response Innate Immune Response Regulation Of Immune Response Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Response To Type I Interferon Interferon-gamma-mediated Signaling Pathway Immune Response Regulation Of Immune System Process Defense Response Cellular Response To Interferon-gamma Megakaryocyte Development Response To Interferon-gamma Regulation Of ERK1 And ERK2 Cascade Platelet Formation Platelet Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Megakaryocyte Differentiation Regulation Of Response To Interferon-gamma Natural Killer Cell Mediated Immunity Myeloid Cell Differentiation Leukocyte Mediated Immunity Positive Regulation Of Immune System Process Immune System Process Positive Regulation Of Cell Activation Regulation Of Cell Adhesion Mediated By Integrin Regulation Of Type I Interferon-mediated Signaling Pathway Regulation Of Lymphocyte Activation Cytokine-mediated Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Cell Activation T Cell Costimulation Signaling Cell Communication Cell Surface Receptor Signaling Pathway Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production Cytotoxic T Cell Differentiation TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Cellular Response To Cytokine Stimulus Regulation Of MAPK Cascade Hemopoiesis Response To Stress Positive Regulation Of Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of ERK1 And ERK2 Cascade See more	Chaperone-mediated Protein Folding Negative Regulation Of Lipid Binding Peroxisome Membrane Biogenesis Protein Folding Chaperone-mediated Protein Transport Protein Import Into Peroxisome Membrane Peroxisomal Membrane Transport Cell-cell Junction Maintenance Peroxisome Fission Protein Targeting To Peroxisome Establishment Of Protein Localization To Peroxisome Cellular Component Maintenance Membrane Biogenesis Synaptic Transmission Synaptic Vesicle Endocytosis Clathrin-mediated Endocytosis Synaptic Vesicle Recycling See more
Tagcloud ?			17q acrocentric anchor backcross centromeric cfa9 cryba1 distally dog galk1 gh1 giemsa hsa17 hsa17p hsa17q interbreed lie loosely mmu11 myl4 nf1 p4hb paint painting spanning syntenic thirds thra1 tk1
Tagcloud (Difference) ?			17q acrocentric anchor backcross centromeric cfa9 cryba1 distally dog galk1 gh1 giemsa hsa17 hsa17p hsa17q interbreed lie loosely mmu11 myl4 nf1 p4hb paint painting spanning syntenic thirds thra1 tk1
Tagcloud (Intersection) ?