ARF5 and ARFIP2

Number of citations of the paper that reports this interaction (PMID 9038142)
26

Data Source:
HPRD (two hybrid, in vitro)

		ARF5	ARFIP2
Gene Name		ADP-ribosylation factor 5	ADP-ribosylation factor interacting protein 2
Image
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Ruffle Cytoplasm Plasma Membrane Cell Cortex Trans-Golgi Network Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding GTP Binding Protein Domain Specific Binding GTP-dependent Protein Binding Rac GTPase Binding Phosphatidylinositol-4-phosphate Binding
	Biological Process	Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport	Movement Of Cell Or Subcellular Component Small GTPase Mediated Signal Transduction Lamellipodium Assembly Actin Cytoskeleton Organization Ruffle Organization
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 23532257)
Protein-Protein Interactions		9 interactors: AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 GGA1 IKBKG PIP5K1A RAB11FIP3	26 interactors: AGTRAP AKT1 APP ARF1 ARF3 ARF5 ARF6 ARL1 CDKN2A CEP63 DTNBP1 HAUS1 HGS ING5 ITGB3BP ITSN1 KRT15 LY6D MAL2 RAC1 RAC2 SNX1 SOCS2 STAT3 TRIM54 USHBP1
Entrez ID		381	23647
HPRD ID		00055	07209
Ensembl ID		ENSG00000004059	ENSG00000132254
Uniprot IDs		A4D0Z3 P84085	B4DUZ3 B4DXH2 P53365
PDB IDs		2B6H	1I49 1I4D 1I4L 1I4T 4DCN
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Cellular Localization Intracellular Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Vesicle-mediated Transport Ruffle Organization Establishment Of Protein Localization Protein Localization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Vesicle Localization Vesicle Localization	Intracellular Signal Transduction Small GTPase Mediated Signal Transduction Signaling Cell Communication Signal Transduction Vesicle-mediated Transport Cell Projection Organization Response To Stimulus Regulation Of Signaling Cellular Response To Stimulus Neurotrophin TRK Receptor Signaling Pathway Organelle Organization Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Signal Transduction Protein Localization Cellular Localization Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Growth Positive Regulation Of Cell Death Apoptotic Process Platelet Activation Protein Transport Programmed Cell Death Regulation Of Hydrogen Peroxide Metabolic Process Blood Coagulation Cell Death Death Cell Division Establishment Of Protein Localization Hemostasis Regulation Of Respiratory Burst Intracellular Transport Establishment Of Localization In Cell Regulation Of Cell Death Positive Regulation Of Lamellipodium Assembly Generation Of Neurons Golgi Vesicle Transport Protein Localization To Organelle Positive Regulation Of Lamellipodium Organization Neurogenesis Cell Projection Morphogenesis Membrane Invagination Cellular Copper Ion Homeostasis Negative Regulation Of JAK-STAT Cascade Cell Part Morphogenesis Positive Regulation Of Signal Transduction Developmental Process
Tagcloud ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually
Tagcloud (Difference) ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually
Tagcloud (Intersection) ?