ARF5 and ASAP2

Number of citations of the paper that reports this interaction (PMID 10022920)
27

Data Source:
HPRD (in vivo)

		ARF5	ASAP2
Gene Name		ADP-ribosylation factor 5	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Plasma Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Plasma Membrane Golgi Cisterna Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Protein Binding Enzyme Activator Activity ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Small GTPase Mediated Signal Transduction Metabolic Process Protein Transport Vesicle-mediated Transport	Regulation Of ARF GTPase Activity Positive Regulation Of Catalytic Activity Positive Regulation Of GTPase Activity
Pathways
Drugs
Diseases
GWAS		Type 2 diabetes ( 23532257)
Protein-Protein Interactions		9 interactors: AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 GGA1 IKBKG PIP5K1A RAB11FIP3	13 interactors: ARF1 ARF5 ARF6 BIN1 GRB2 ITSN1 PACSIN3 PTK2B PXN RAN REPS2 SH3KBP1 THSD7A
Entrez ID		381	8853
HPRD ID		00055	04820
Ensembl ID		ENSG00000004059	ENSG00000151693
Uniprot IDs		A4D0Z3 P84085	O43150
PDB IDs		2B6H
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Cellular Localization Intracellular Transport Intracellular Protein Transport Cellular Protein Localization Protein Transport Vesicle-mediated Transport Ruffle Organization Establishment Of Protein Localization Protein Localization Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Positive Regulation Of NK T Cell Differentiation Establishment Of Vesicle Localization Vesicle Localization	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Vesicle-mediated Transport Small GTPase Mediated Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Component Organization Regulation Of Endocytosis Enzyme Linked Receptor Protein Signaling Pathway Cytoskeleton Organization Cell Projection Organization Endocytosis Intracellular Signal Transduction Transport Positive Regulation Of Actin Filament Polymerization Signal Complex Assembly Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Protein Polymerization Regulation Of Vesicle-mediated Transport Signal Transduction Regulation Of Actin Filament-based Process Movement Of Cell Or Subcellular Component Signaling Regulation Of Cell Shape Cell Communication Focal Adhesion Assembly Positive Regulation Of Protein Complex Assembly Cell Differentiation Regulation Of Actin Filament Polymerization Regulation Of Cytoskeleton Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Viral Process Regulation Of Actin Filament Length Adherens Junction Assembly Negative Regulation Of Endocytosis Cell-substrate Junction Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Cellular Response To Stimulus Regulation Of Signaling Organelle Organization Positive Regulation Of Cellular Component Biogenesis Establishment Of Organelle Localization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Adherens Junction Organization Positive Regulation Of Metabolic Process Generation Of Neurons
Tagcloud ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually	affy cdkn2a coexpressed coexpression constructed contructed david degs differential differentially disturbed dlk1 downloaded enrichment exploring gse26966 hub inositol itga4 mpp2 network networks obvious omnibus package phosphatidylinositol pituitary screened software
Tagcloud (Difference) ?		arabidopsis arfs aspect aux auxin back broadly coincide correct entire feed iaa indispensable influences modules monopteros mp nearly onto redundantly repressors retardation steroid subclades subsets thaliana transduction virtually	affy cdkn2a coexpressed coexpression constructed contructed david degs differential differentially disturbed dlk1 downloaded enrichment exploring gse26966 hub inositol itga4 mpp2 network networks obvious omnibus package phosphatidylinositol pituitary screened software
Tagcloud (Intersection) ?