KCNK3 and S100A10

Number of citations of the paper that reports this interaction (PMID 12198146)
33

Data Source:
BioGRID (two hybrid, pull down)
HPRD (two hybrid, in vivo, in vitro)

		KCNK3	S100A10
Gene Name		potassium channel, two pore domain subfamily K, member 3	S100 calcium binding protein A10
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extrinsic Component Of Plasma Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Ion Channel Activity Open Rectifier Potassium Channel Activity Potassium Channel Activity Protein C-terminus Binding Potassium Ion Leak Channel Activity Protein Homodimerization Activity S100 Protein Binding Protein Heterodimerization Activity	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Ion Channel Binding
	Biological Process	Potassium Ion Transport Synaptic Transmission Brain Development Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Response To Drug Negative Regulation Of Cytosolic Calcium Ion Concentration Cellular Response To Zinc Ion Cellular Response To Hypoxia Potassium Ion Transmembrane Transport Cochlea Development	Membrane Raft Assembly Membrane Budding Positive Regulation Of Rac GTPase Activity Positive Regulation Of Binding Protein Heterotetramerization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		TWIK-releated acid-sensitive K+ channel (TASK) Tandem pore domain potassium channels Potassium Channels	Dissolution of Fibrin Clot Orphan transporters
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: COPB1 S100A10 SFN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ	13 interactors: ANXA2 ANXA7 BAD CDK16 COPS6 CTSB FSHR KCNK3 PLA2G4C PLG SETDB1 TRPV5 TRPV6
Entrez ID		3777	6281
HPRD ID		04451	00232
Ensembl ID			ENSG00000197747
Uniprot IDs		O14649	P60903
PDB IDs			1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Positive Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Membrane Organization Positive Regulation Of Intracellular Transport Apoptotic Signaling Pathway Regulation Of Intracellular Transport Regulation Of Organelle Organization Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Cellular Protein Localization Regulation Of Protein Localization Establishment Of Protein Localization Intracellular Protein Transport Apoptotic Process Programmed Cell Death Regulation Of Cellular Localization Cell Death Death Protein Localization Regulation Of Cellular Component Organization Positive Regulation Of Signal Transduction Protein Transport Cellular Localization Regulation Of Apoptotic Process Intracellular Transport Regulation Of Cell Death Protein Targeting Regulation Of Signal Transduction Substantia Nigra Development Intracellular Signal Transduction Regulation Of Signaling Neural Nucleus Development Establishment Of Localization In Cell Negative Regulation Of Protein Dephosphorylation Midbrain Development Transport Hippo Signaling Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Negative Regulation Of Dephosphorylation Organelle Organization	Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Cellular Homeostasis Reproductive Process Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Calcium Ion Homeostasis Homeostatic Process Calcium Ion Homeostasis Cellular Response To Chromate Response To Metal Ion Extracellular Matrix Organization Extracellular Structure Organization Chemical Homeostasis Regulation Of Blood Coagulation Positive Regulation Of Mitochondrial Membrane Potential Suppression By Virus Of Host Apoptotic Process Extracellular Matrix Disassembly Cellular Metal Ion Homeostasis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Anatomical Structure Development Protein Tetramerization Cellular Cation Homeostasis Mononuclear Cell Migration Cellular Response To Oxygen Levels Cellular Ion Homeostasis Response To Calcium Ion Catabolic Process Metal Ion Homeostasis Regulation Of Wound Healing Response To Inorganic Substance Reproductive Structure Development Reproductive System Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Apoptotic Process By Virus Glucose Catabolic Process Positive Regulation Of Fibrinolysis Cellular Response To Inorganic Substance Positive Regulation Of Type B Pancreatic Cell Development Follicle-stimulating Hormone Signaling Pathway Cellular Chemical Homeostasis Single Organism Reproductive Process Establishment Of Localization In Cell Organ Development System Development Developmental Process Ion Homeostasis Positive Regulation Of Glucokinase Activity
Tagcloud ?		attenuation channels conductance dag determinants diacylglycerol downstream excitability galphaq gated gpcr gpcrs hormones initiated ip3 k2p kcnk9 links lipase messengers p2 phospholipase plc pore potassium subclass task transients transmitters	annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions
Tagcloud (Difference) ?		attenuation channels conductance dag determinants diacylglycerol downstream excitability galphaq gated gpcr gpcrs hormones initiated ip3 k2p kcnk9 links lipase messengers p2 phospholipase plc pore potassium subclass task transients transmitters	annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions
Tagcloud (Intersection) ?