AUP1 and RNF11

Number of citations of the paper that reports this interaction (PMID 15231748)
65

Data Source:
BioGRID (two hybrid)

		AUP1	RNF11
Gene Name		ancient ubiquitous protein 1	ring finger protein 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Ubiquitin Ligase Complex Nucleus Early Endosome Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	DNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding
	Biological Process		Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Protein Autoubiquitination
Pathways
Drugs
Diseases
GWAS			Ventricular conduction ( 21076409)
Protein-Protein Interactions		7 interactors: ITGA1 ITGA2 ITGA2B ITGA5 ITGAM ITGAV RNF11	68 interactors: AKT1 ANKRD13A APP ASCC2 AUP1 CALCOCO2 CBLB CCDC127 DCUN1D1 EPN1 EPN2 EPN3 EPS15 ERCC6 GGA1 GGA2 GGA3 HERC1 HERC2 HUWE1 IKBKG ITCH MYO6 NEDD4 NEDD4L OPTN PDCD6IP POLI PTPRC QARS RABGEF1 RIPK1 RNF168 RNF216 RPS27A SDCBP SMURF1 SMURF2 SNRNP70 SPRTN STAM2 STAMBP STAMBPL1 TAX1BP1 TNFAIP3 TNIP1 TOM1L2 UBA52 UBAC1 UBB UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBQLN2 UBQLN4 USP5 WWP1 WWP2 ZFYVE16 ZFYVE9 ZNF350
Entrez ID		550	26994
HPRD ID		03892	09955
Ensembl ID		ENSG00000115307	ENSG00000123091
Uniprot IDs		Q9Y679	Q9Y3C5
PDB IDs		2EKF
Enriched GO Terms of Interacting Partners?		Integrin-mediated Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Blood Coagulation Hemostasis Cell-substrate Adhesion Regulation Of Body Fluid Levels Wound Healing Chemotaxis Response To Wounding Axon Guidance Cell-matrix Adhesion Cell Adhesion Axonogenesis Locomotion Axon Development Cell Morphogenesis Involved In Neuron Differentiation Leukocyte Migration Neuron Projection Morphogenesis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Differentiation Neurogenesis Neuron Projection Development Cell Migration Cell Projection Morphogenesis Positive Regulation Of Cell Migration Cell Part Morphogenesis Positive Regulation Of Cell Motility Cell Development Response To External Stimulus Positive Regulation Of Cellular Component Movement Cell Motility Positive Regulation Of Locomotion Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Nervous System Development Formation Of Primary Germ Layer Cell Adhesion Mediated By Integrin Single Organismal Cell-cell Adhesion Regulation Of Cell Migration Regulation Of Cell Motility Gastrulation Heterotypic Cell-cell Adhesion Regulation Of Locomotion Generation Of Neurons Regulation Of Cellular Component Movement Cellular Extravasation Positive Regulation Of Phosphatase Activity	Protein Ubiquitination Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Catabolic Process Cellular Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Cellular Macromolecule Catabolic Process Positive Regulation Of Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Proteolysis Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of Innate Immune Response Regulation Of Protein Catabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Protein Modification Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Negative Regulation Of Signaling Toll-like Receptor 4 Signaling Pathway Protein K63-linked Ubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response TRIF-dependent Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Cellular Protein Metabolic Process Proteasomal Protein Catabolic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Protein Metabolic Process Negative Regulation Of Type I Interferon Production Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Immune Response-regulating Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Intracellular Transport Cellular Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Transforming Growth Factor Beta Receptor Signaling Pathway Protein Metabolic Process Intracellular Protein Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Innate Immune Response Cellular Response To Stimulus
Tagcloud ?		abundance affects ancient associates conjugating connection cue dislocation droplet droplets endoplasmic engagement facilitates hrd1 impairs involves lipid localizes misfolded physically polyubiquitylation proteasome quality recruit reticulum sel1l ube2g2 ubiquitin ubiquitous
Tagcloud (Difference) ?		abundance affects ancient associates conjugating connection cue dislocation droplet droplets endoplasmic engagement facilitates hrd1 impairs involves lipid localizes misfolded physically polyubiquitylation proteasome quality recruit reticulum sel1l ube2g2 ubiquitin ubiquitous
Tagcloud (Intersection) ?